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6-Fluorohexan-1-ol

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Identification
Molecular formula
C6H13FO
CAS number
373-39-5
IUPAC name
6-fluorohexan-1-ol
State
State

At room temperature, 6-Fluorohexan-1-ol is a liquid. It remains in the liquid state under standard laboratory conditions and is typically handled as a liquid chemical.

Melting point (Celsius)
-44.00
Melting point (Kelvin)
229.15
Boiling point (Celsius)
164.00
Boiling point (Kelvin)
437.15
General information
Molecular weight
120.16g/mol
Molar mass
120.1630g/mol
Density
1.0001g/cm3
Appearence

6-Fluorohexan-1-ol is a clear, colorless liquid. It is an organic compound that is typically transparent and may have a slight characteristic odor similar to other hexanol derivatives.

Comment on solubility

Solubility of 6-fluorohexan-1-ol

6-fluorohexan-1-ol, with its unique functional groups, exhibits interesting solubility characteristics. The presence of the hydroxyl group (-OH) contributes to its overall *polarity*, which can enhance its solubility in a variety of solvents. Here’s a closer look at its solubility:

  • Solubility in Water: The hydroxyl group allows 6-fluorohexan-1-ol to engage in hydrogen bonding with water molecules, making it reasonably soluble in water.
  • Solubility in Organic Solvents: This compound may also dissolve well in polar organic solvents such as ethanol and acetone due to similar polar characteristics.
  • Temperature Influence: As with many organic compounds, solubility may increase with an increase in temperature, facilitating better interactions between solute and solvent.

However, *factors that affect solubility* include:

  1. The length of the hydrocarbon chain.
  2. The presence of the fluorine atom may influence the compound's overall polarity and solid-state interactions.
  3. The formation of intermolecular forces, such as van der Waals interactions.

Overall, while 6-fluorohexan-1-ol has beneficial solubility features due to its functional groups, the specific interactions and environmental conditions should be taken into account for practical applications.

Interesting facts

Interesting Facts about 6-Fluorohexan-1-ol

6-Fluorohexan-1-ol is a fascinating compound that falls under the category of alcohols. This chemical is notable for several reasons, making it a subject of interest for both researchers and students in the field of chemistry.

Key Features and Uses

  • Fluorinated Compound: The presence of a fluorine atom in 6-fluorohexan-1-ol significantly alters its chemical properties. Fluorine enhances the compound's lipophilicity, which aids in its ability to interact with biological membranes.
  • Versatile Intermediate: This compound can serve as a valuable intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical industry. Its unique structure makes it an ideal precursor for complex molecular architectures.
  • Potential Biological Activity: The incorporation of the fluorine atom could impart interesting biological activities and properties to the compound, which can be explored in medicinal chemistry.

Chemical Significance

Understanding the properties of 6-fluorohexan-1-ol can provide insights into:

  • Reactivity: How the fluorine affects the reactivity of the alcohol group and the overall molecular behavior in different reactions.
  • Stability: The stability of the compound under various conditions and its ability to withstand chemical reactions.
  • Interactions: The interaction with enzymes and other biological molecules, which is critically important in drug design and development.

As noted by chemist John McBain, "Fluorinated compounds often display unusual behaviors that can lead to exciting innovations in chemical science." Exploring these behaviors in compounds like 6-fluorohexan-1-ol may pave the way for groundbreaking developments in various fields.

In summary, 6-fluorohexan-1-ol is more than just a simple alcohol; its unique characteristics and potential applications make it a compelling topic of study within organic and medicinal chemistry.

Synonyms
6-fluoro-1-hexanol
373-32-0
6-fluorohexan-1-ol
HEXANOL, 6-FLUORO-
6-Fluorohexanol
omega-Fluorohexanol
6-fluoro-hexan-1-ol
BRN 1732414
DTXSID00190753
SCHEMBL180223
DTXCID40113244
AKOS006272607
DB-229531
EN300-216247
G77548
832-084-7