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6-Fluorohexanal

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Identification
Molecular formula
C6H11FO
CAS number
403-43-0
IUPAC name
6-fluorohexanal
State
State

At room temperature, 6-Fluorohexanal is a liquid. Like many aldehydes, it remains liquid under standard temperature and pressure conditions.

Melting point (Celsius)
-70.00
Melting point (Kelvin)
203.20
Boiling point (Celsius)
148.10
Boiling point (Kelvin)
421.30
General information
Molecular weight
116.14g/mol
Molar mass
116.1420g/mol
Density
0.9268g/cm3
Appearence

6-Fluorohexanal is a clear, colorless liquid. Like other aliphatic aldehydes, it has a strong, pungent odor that is often characteristic of aldehydes. It should be handled with care as fumes may be irritating.

Comment on solubility

Solubility of 6-fluorohexanal

6-fluorohexanal, possessing the molecular formula C6H11FO, exhibits distinct solubility characteristics that are influenced by its unique structure. Understanding the solubility of this compound is crucial for its applications in various fields, including pharmaceuticals and organic synthesis. Here are some key points regarding its solubility:

  • Polarity: The presence of the fluorine atom renders 6-fluorohexanal a polar molecule, which enhances its ability to interact with polar solvents, such as water.
  • Solvent Compatibility: Due to its polarity, 6-fluorohexanal is likely to exhibit moderate solubility in water and other polar solvents. This makes it suitable for reactions in aqueous environments.
  • Hydrophobic Effects: While the long carbon chain contributes to hydrophobic interactions, the fluoro substituent plays a significant role in solubility, balancing the hydrophobic and hydrophilic properties.
  • Temperature Dependency: Like many organic compounds, the solubility of 6-fluorohexanal may vary with temperature, generally increasing with higher temperatures due to enhanced molecular movement and interaction.

In summary, the solubility of 6-fluorohexanal reflects a unique interplay between its molecular structure and environmental conditions. As stated, "The solubility of organic compounds is a crucial aspect to consider for their usability and efficacy in various applications."

Interesting facts

Interesting Facts about 6-Fluorohexanal

6-Fluorohexanal is a fascinating compound that serves as a valuable building block in organic chemistry, particularly in the fields of medicinal chemistry and materials science. Here are some notable aspects:

  • Fluorine Substitution: The presence of a fluorine atom in this molecule significantly influences its reactivity and biological properties. Fluorine is known for enhancing the lipophilicity of compounds, which can improve their ability to permeate cell membranes. This is particularly useful in drug design as it can lead to more effective pharmaceutical agents.
  • Versatile Intermediate: 6-Fluorohexanal is often used as an intermediate in the synthesis of various organic compounds. Its unique structure allows for the preparation of more complex molecules, making it a vital component in synthetic pathways.
  • Flavor and Fragrance Industries: Given its aldehyde functional group, compounds like 6-fluorohexanal can possess distinct structural analogs with impactful olfactory properties. Such compounds are often explored in the flavor and fragrance industries for their potential applications in producing unique scents and flavors.
  • Research Opportunities: The exploration of 6-fluorohexanal and its derivatives can lead to exciting discoveries in the development of agrochemicals and other specialty chemicals, as modifications to its structure can result in vastly different properties.
  • Biological Activity: Scientific studies suggest that compounds with the fluorine moiety can exhibit interesting biological activities, making 6-fluorohexanal a candidate for further research in pharmacology.

As a compound that embodies the principles of halogen incorporation in organic synthesis, 6-fluorohexanal holds promise not only for its immediate applications but also as a gateway to exploring new chemical territories. Its study illustrates the profound impact that seemingly small changes in molecular structure can have on the properties and behaviors of chemical compounds.

Synonyms
6-Fluorohexanal
HEXANAL, 6-FLUORO-
373-33-1
BRN 1700592
DTXSID60190754
4-01-00-03297 (Beilstein Handbook Reference)
SCHEMBL834167
DTXCID00113245
EN300-1830743