Interesting facts
Interesting Facts about 6-Fluorohexane-1-sulfonyl Chloride
6-Fluorohexane-1-sulfonyl chloride is a compound that plays a significant role in the field of organic chemistry, particularly in the synthesis of various pharmaceutical intermediates. As a sulfonyl chloride, it is characterized by a sulfonyl group attached to a hexane chain that carries a fluorine atom at the sixth position. Here are some fascinating insights about this compound:
- Reactivity: Sulfonyl chlorides like 6-fluorohexane-1-sulfonyl chloride are known for their high reactivity, particularly in nucleophilic substitution reactions. They can react with nucleophiles such as amines and alcohols to form sulfonamides and sulfonate esters, which are valuable intermediates in pharmaceutical chemistry.
- Fluorine's Impact: The presence of fluorine enhances the electronic properties of the compound, influencing its reactivity and stability. Fluorine substituents can alter the lipophilicity of molecules, affecting their bioavailability and interactions in biological systems.
- Applications: This compound serves as a key building block in the synthesis of drugs, agrochemicals, and other specialized organic compounds. Its utility in modifying molecular frameworks makes it a valuable reagent in research laboratories.
- Safety Considerations: Due to the presence of the sulfonyl chloride functional group, proper handling and safety precautions are essential. The compound can be corrosive and may react violently with water, necessitating careful management in a controlled environment.
In summary, 6-fluorohexane-1-sulfonyl chloride exemplifies how relatively simple organic compounds can have significant implications in synthetic chemistry and drug discovery. Its unique properties and reactivity make it an intriguing subject for both students and professionals in the field.
Synonyms
372-69-0
6-Fluorohexanesulphonyl chloride
HEXANESULFONYL CHLORIDE, 6-FLUORO-
BRN 1766094
DTXSID40190691
6-fluorohexane-1-sulfonyl chloride
DTXCID80113182
AKOS006335705
Solubility of 6-Fluorohexane-1-sulfonyl chloride
6-Fluorohexane-1-sulfonyl chloride is a fascinating compound notable for its solubility characteristics. Understanding the solubility behavior of this substance is crucial for its applications in various chemical processes.
Key observations regarding its solubility include:
In practice, conducting reactions or applications outside of its solubility range can lead to challenges. As a rule of thumb, consider the solvent’s properties when working with compounds like 6-fluorohexane-1-sulfonyl chloride to ensure optimal functionality and yield.
Ultimately, the solubility profile of 6-fluorohexane-1-sulfonyl chloride emphasizes the balance between polar and non-polar interactions, making solvent selection a critical aspect of its utilization in the laboratory.