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6-Fluorohexane-1-thiol

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Identification
Molecular formula
C6H13FS
CAS number
68171-74-8
IUPAC name
6-fluorohexane-1-thiol
State
State

At room temperature, 6-Fluorohexane-1-thiol is a liquid.

Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.15
Boiling point (Celsius)
161.00
Boiling point (Kelvin)
434.15
General information
Molecular weight
136.22g/mol
Molar mass
136.2160g/mol
Density
0.9553g/cm3
Appearence

6-Fluorohexane-1-thiol is typically a clear, colorless to pale yellow liquid with a distinct thiol odor, which is often described as unpleasant or resembling rotten eggs.

Comment on solubility

Solubility of 6-fluorohexane-1-thiol

6-fluorohexane-1-thiol, with its unique structure, showcases interesting solubility characteristics that are influenced by both its polar and non-polar components. Here are some key points to consider:

  • Polarity: The presence of the thiol group (-SH) adds a certain degree of polarity to the molecule, which can enhance solubility in polar solvents.
  • Hydrophobic Tail: The hexane component of the compound is largely hydrophobic, which may lead to lower solubility in water, a polar solvent.
  • Solvent Compatibility: 6-fluorohexane-1-thiol is expected to be more soluble in organic solvents such as ethanol, acetone, and chloroform, rather than in water.
  • Temperature Effects: Typically, increasing temperature can increase the solubility of organic compounds; thus, elevated temperatures may enhance the solubility of this thiol in organic solvents.

In summary, while 6-fluorohexane-1-thiol exhibits limited solubility in water due to its hydrophobic nature, it demonstrates a greater affinity for organic solvents, making it a versatile compound in various chemical applications. As with many chemical compounds, the solubility greatly depends on the surrounding environment and solvent choice.

Interesting facts

Interesting Facts about 6-Fluorohexane-1-thiol

6-Fluorohexane-1-thiol is an intriguing compound that falls under the category of thiols, which are characterized by the presence of a sulfur atom attached to a carbon chain. Here are some noteworthy aspects of this compound:

  • Fluorine Influence: The incorporation of fluorine into the molecular structure significantly affects the compound's reactivity and physical properties. Fluorine is known for its electronegativity, which can enhance the compound's ability to participate in various chemical reactions.
  • Applications in Organic Synthesis: 6-Fluorohexane-1-thiol can be utilized as a building block in organic synthesis. Its functional groups allow for further modification, making it valuable in creating more complex molecules.
  • Potential in Medicinal Chemistry: Researchers are increasingly interested in fluorinated compounds for their unique biological properties. The presence of thiol groups can contribute to the biological activity of the molecule, which could have implications in drug design.
  • Odor and Flavor Chemistry: Thiols are often associated with strong odors, and 6-fluorohexane-1-thiol is no exception. Its distinct scent makes it a compound of interest in the fields of aroma synthesis and flavor chemistry.
  • Environmental Considerations: Understanding the behavior of fluorinated thiols in the environment is critical, as fluorinated compounds can exhibit unique environmental persistence. This raises important questions about their impact on ecosystems.

In summary, 6-fluorohexane-1-thiol is not just a simple compound; it opens up avenues for research and application across various scientific fields. As chemists continue to explore its properties and potential uses, the excitement surrounding this compound is likely to grow.

Synonyms
HEXANETHIOL, 6-FLUORO-
6-Fluorohexyl mercaptan
408-09-3
Mercaptan, 6-fluorohexyl-
BRN 1732504
DTXSID60193785
4-01-00-01707 (Beilstein Handbook Reference)
SCHEMBL516591
DTXCID00116276