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Berberine bromide

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Identification
Molecular formula
C20H18BrNO4
CAS number
7689-71-6
IUPAC name
6-isopentyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;bromide
State
State

At room temperature, berberine bromide is found in a solid state, usually as a powder or small crystals.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
422.37g/mol
Molar mass
422.3670g/mol
Density
1.3000g/cm3
Appearence

Berberine bromide typically appears as a yellow to brownish-yellow powder or crystalline solid. Its vibrant coloration is due to its conjugated system of double bonds.

Comment on solubility

Solubility of 6-isopentyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium Bromide

The solubility of 6-isopentyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide can be complex due to its unique structure. Various factors influence its solubility, which can primarily be categorized as follows:

  • Polarity: The presence of various functional groups such as the isopentyl and methoxy may contribute to both polar and non-polar interactions.
  • Hydrophilicity vs Hydrophobicity: The methoxy group tends to enhance solubility in polar solvents, while the isopentyl side chain may make it more soluble in non-polar solvents.
  • Ionization: The quaternary ammonium nature of the compound indicates that it may be ionic and thus more soluble in aqueous solutions.

In practical terms, one might observe:

  1. High solubility in organic solvents: Due to the non-polar aspects of the isopentyl chain.
  2. Variable behavior in water: Depending on the pH and the ionic strength of the solution, solubility could vary significantly.

In summary, the solubility of this compound is likely to exhibit both versatility and complexity, influenced by the interplay between its functional groups and the solvent environment. Understanding these solubility characteristics is essential for its effective application in various chemical processes and formulations.

Interesting facts

Interesting Facts about 6-isopentyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide

This compound is a fascinating example of the intricate world of isoquinolines, which are a type of alkaloid known for their diverse biological activities. The structure of this compound, specifically its unique dioxolo ring system, suggests potential pharmacological significance. Here are some engaging facts:

  • Alkaloid Potential: Isoquinolines, including this compound, are frequently studied for their medicinal properties. Compounds like these can exhibit a range of biological activities, from anticancer to antimicrobial effects.
  • Structural Complexity: The presence of a dioxolo group gives this molecular structure a distinct feature, allowing it to interact differently with biological systems than simpler compounds.
  • Rarity in Nature: Compounds of this structural type are not commonly found in nature, making synthetic variants significantly valuable for research and medicinal chemistry.
  • Potential Uses: Research has indicated that isoquinoline derivatives can serve as important components in drug discovery, particularly in the development of therapies for various diseases, including neurological disorders.

Given its complex nature, this compound serves as a reminder of the endless possibilities found within chemical research. As stated by renowned chemist Sir Derek Barton, "Chemistry is the science of change," and the exploration of such compounds exemplifies this transformative essence in scientific inquiry.

As research progresses, it is exciting to consider the potential applications and discoveries that may arise from further studies of 6-isopentyl-4-methoxy-[1,3]dioxolo[4,5-g]isoquinolin-6-ium bromide!

Synonyms
6-Isopentyl-4-methoxy-1,3-dioxolo(4,5-g)isoquinolinium bromide
15270-27-6
1,3-DIOXOLO(4,5-g)ISOQUINOLINIUM, 6-ISOPENTYL-4-METHOXY-, BROMIDE
DTXSID00934578
Methyl[6-(3-methylbutyl)-2H-[1,3]dioxolo[4,5-g]isoquinolin-4(6H)-ylidene]oxidanium bromide