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6-Methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol

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Identification
Molecular formula
C20H19NO2
CAS number
226905-08-0
IUPAC name
6-methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol
State
State

At room temperature, 6-Methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol is typically in the form of a solid crystalline powder. It remains stable under typical storage and handling conditions.

Melting point (Celsius)
220.50
Melting point (Kelvin)
493.65
Boiling point (Celsius)
550.70
Boiling point (Kelvin)
823.85
General information
Molecular weight
327.41g/mol
Molar mass
327.4060g/mol
Density
1.1902g/cm3
Appearence

6-Methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol appears as a crystalline solid, usually colorless to light yellow. The compound is usually provided in a pure solid form and should be stored away from light to prevent any possible degradation or discoloration.

Comment on solubility

Solubility of 6-methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol

6-methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol (C20H19NO2) presents intriguing properties regarding its solubility, reflecting its unique molecular structure. Here are some key points to consider:

  • Solvent Dependence: The solubility of this compound may significantly vary depending on the solvent used. It tends to be more soluble in organic solvents such as methanol or ethanol compared to water.
  • Polarity: With functional groups that enhance its hydrophobic character, 6-methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol exhibits limited solubility in polar solvents.
  • Potential Formation of Hydrogen Bonds: The presence of the hydroxyl (-OH) group suggests a propensity for hydrogen bonding, which can influence solubility in certain environments.
  • Temperature Influence: As is common with many organic compounds, an increase in temperature can enhance solubility, allowing for a better dissolution rate in chosen solvents.

In conclusion, the solubility characteristics of 6-methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol reflect a combination of its molecular design and environmental conditions. Understanding these factors is crucial for applications in both research and industrial processes.

Interesting facts

Interesting Facts about 6-Methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol

6-Methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol is a fascinating compound primarily due to its structural complexity and potential applications in medicinal chemistry. Here are some noteworthy points:

  • Structural Diversity: This compound integrates a tetralin moiety with both a methoxy group and a pyridine ring, showcasing a rich structural diversity that may contribute to its biological activity.
  • Potential Biological Activity: Compounds structurally related to this one have been studied for their potential as therapeutic agents, particularly in neurology and psychiatry. The presence of the pyridine ring is often associated with enhanced receptor interactions.
  • Focus on Methoxy Substituents: The methoxy group (–OCH3) can significantly influence the compound's reactivity and pharmacokinetics. This substitution often enhances lipid solubility, aiding in better absorption in biological systems.
  • Role in Research: Compounds similar to 6-methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol are frequently explored for their effects on neurotransmitter systems, making them valuable in the study of disorders such as depression and anxiety.

In summary, 6-methoxy-1-phenyl-2-(3-pyridyl)tetralin-1-ol exemplifies how intricate structural characteristics can lead to significant biological implications, making it a compound of interest for chemists and pharmacologists alike.

Synonyms
6-Methoxy-1-phenyl-2-(3-pyridyl)-1,2,3,4-tetrahydro-1-naphthol
10059-83-3
BRN 1551834
1-NAPHTHOL, 1,2,3,4-TETRAHYDRO-6-METHOXY-1-PHENYL-2-(3-PYRIDYL)-
DTXSID00905607
6-Methoxy-1-phenyl-2-(pyridin-3-yl)-1,2,3,4-tetrahydronaphthalen-1-ol