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6-Methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol

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Identification
Molecular formula
C20H19NO2
CAS number
/132485-29-5
IUPAC name
6-methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol
State
State

At room temperature, 6-Methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol is in a solid state as it is typically encountered as a crystalline solid. This form is common for many organic compounds that comprise large, complex structures.

Melting point (Celsius)
137.50
Melting point (Kelvin)
410.60
Boiling point (Celsius)
421.10
Boiling point (Kelvin)
694.10
General information
Molecular weight
315.38g/mol
Molar mass
315.3930g/mol
Density
1.1812g/cm3
Appearence

This compound typically appears as a crystalline solid. It may be presented as either white or off-white in color, indicating its purity level. The compound's crystalline nature suggests that it features a defined structure that repeats periodically, contributing to its solid-state at room temperature.

Comment on solubility

Solubility of 6-methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol

The solubility of 6-methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol can be influenced by several factors, primarily its chemical structure and interactions with solvents. Here are some key points to consider:

  • Polar vs Non-Polar Solvents: This compound contains both hydrophobic (non-polar) and hydrophilic (polar) regions, which suggests that it may exhibit solubility in a range of solvents. It tends to be more soluble in polar organic solvents, such as ethanol and methanol, while potentially being less soluble in non-polar solvents like hexane.
  • pH Sensitivity: The phenolic group (–OH) and the pyridine moiety may contribute to its solubility characteristics through interactions with the solvent. Changes in pH can alter the protonation state of the pyridine, affecting solubility.
  • Temperature Impacts: As with many organic compounds, an increase in temperature generally leads to an increase in solubility, making aqueous solutions more favorable for dissolution at higher temperatures.

In conclusion, while 6-methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol is expected to be soluble in certain polar solvents, its unique structure introduces nuances that can affect solubility depending on the environmental conditions. Understanding these aspects is key for applications in pharmacology and materials science.

Interesting facts

Interesting Facts about 6-Methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol

6-Methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol, often abbreviated in various studies and discussions, is a fascinating compound with intriguing properties and applications in the field of medicinal chemistry. Here are some key highlights:

  • Structure and Composition: This compound features a unique structure that combines a tetralin core with a methoxy group and a phenyl-pyridyl substituent, making it a vital player in exploring structure-activity relationships in drug design.
  • Potential Pharmacological Activities: Research indicates that compounds with similar structures may exhibit significant interactions with neurotransmitter systems, including dopamine and serotonin, which brings attention to their potential in treating neurological disorders.
  • Scientific Investigations: The compound has been the subject of various studies focused on its effects as a possible therapeutic agent. Scientists are particularly interested in its role as an agonist or antagonist in the central nervous system.
  • Research Utility: Beyond its biological relevance, this compound serves as a useful reference in chemical synthesis processes, providing insights into the synthetic routes and methodologies that chemists can employ to fabricate complex organic molecules.
  • Synergistic Effects: What makes 6-methoxy-2-phenyl-1-(4-pyridyl)tetralin-1-ol particularly exciting is the potential synergistic effects observed when combined with other compounds, opening new avenues for combination therapies.

As research progresses, the scientific community continues to explore the vast potential that this compound holds. Its multifaceted nature not only spurs curiosity among chemists but also fosters hope for advancements in therapeutic applications.

In the words of one pioneering chemist, "The beauty of studying complex organic compounds lies in the endless possibilities they present for innovation and discovery."

Synonyms
1,2,3,4-Tetrahydro-6-methoxy-2-phenyl-1-(4-pyridyl)-1-naphthol
9Z07SMA3IO
5205-72-1
1-NAPHTHOL, 1,2,3,4-TETRAHYDRO-6-METHOXY-2-PHENYL-1-(4-PYRIDYL)-
BRN 1551835
UNII-9Z07SMA3IO
6-Methoxy-2-phenyl-1-(4-pyridyl)-1,2,3,4-tetrahydro-1-naphthol
DTXSID50966420
Q27273396
6-methoxy-2-phenyl-1-(pyridin-4-yl)-1,2,3,4-tetrahydronaphthalen-1-ol
1-NAPHTHALENOL, 1,2,3,4-TETRAHYDRO-6-METHOXY-2-PHENYL-1-(4-PYRIDINYL)-