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Quinidine

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Identification
Molecular formula
C20H24N2O2
CAS number
56-54-2
IUPAC name
(6-methoxy-4-quinolyl)-[(2R,4R,5R)-5-vinylquinuclidin-2-yl]methanol
State
State

At room temperature, Quinidine is typically in a solid state.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
685.50
Boiling point (Kelvin)
958.65
General information
Molecular weight
324.43g/mol
Molar mass
324.4330g/mol
Density
1.3400g/cm3
Appearence

Quinidine usually appears as a white crystalline powder.

Comment on solubility

Solubility of (6-methoxy-4-quinolyl)-[(2R,4R,5R)-5-vinylquinuclidin-2-yl]methanol

The compound (6-methoxy-4-quinolyl)-[(2R,4R,5R)-5-vinylquinuclidin-2-yl]methanol, with the chemical formula C20H24N2O2, exhibits a unique profile in terms of solubility. Understanding its solubility characteristics is essential for various applications, particularly in pharmaceutical contexts. Here are some key points regarding its solubility:

  • Polar Nature: Due to the presence of a hydroxyl (-OH) group in its structure, this compound is expected to have some polar characteristics.
  • Solvent Interaction: The solubility may vary significantly depending on the solvent used, with increased solubility likely in polar solvents like methanol or ethanol.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules can enhance its solubility in aqueous environments.
  • Stability Considerations: While solubility is a critical factor, the stability of the compound in solution should not be overlooked, as it may affect practical solubility.
  • Temperature Dependence: Solubility is also temperature-dependent; higher temperatures can lead to increased solubility in many cases.

It is important to note that while general trends provide some insight, the solubility of (6-methoxy-4-quinolyl)-[(2R,4R,5R)-5-vinylquinuclidin-2-yl]methanol may require experimental evaluation for precise quantification.

Interesting facts

Interesting Facts about (6-methoxy-4-quinolyl)-[(2R,4R,5R)-5-vinylquinuclidin-2-yl]methanol

This compound, known for its intricate molecular structure, is a fascinating example of how chemical manipulation can lead to unique properties and potential applications. Here are some intriguing aspects:

  • Pharmacological Potential: Compounds like (6-methoxy-4-quinolyl)-[(2R,4R,5R)-5-vinylquinuclidin-2-yl]methanol are often studied for their pharmacological properties. The presence of the quinolinyl group suggests potential interactions with biological systems that could be beneficial for drug development.
  • Quinolines in Medicine: Quinolines are a versatile class of compounds in medicinal chemistry. They are known for their antimicrobial, anticancer, and antimalarial properties, making them significant in the search for new therapeutic agents.
  • Chiral Centers: The compound contains several chiral centers, particularly at the quinuclidine moiety. The stereochemistry plays a crucial role in determining the biological activity of the compound, which can vary significantly between different enantiomers.
  • Vinyl Group Chemistry: The vinyl group (–CH=CH2) not only contributes to the overall reactivity of the compound but also opens avenues for further chemical modifications through traditional organic reactions such as polymerization or cross-coupling.
  • Implications in Material Science: Beyond medicinal applications, the structural features of this compound might lend themselves well to materials science. The unique arrangement of functional groups can facilitate interactions favorable for applications in organic electronics or as intermediates in synthesizing novel materials.

In conclusion, (6-methoxy-4-quinolyl)-[(2R,4R,5R)-5-vinylquinuclidin-2-yl]methanol embodies the intricate interplay between structure and function in organic chemistry. As research continues to unfold, compounds like these pave the way for innovations in various scientific fields.