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Halofantrine

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Identification
Molecular formula
C26H30ClNO2
CAS number
69756-53-2
IUPAC name
(6-methoxy-4-quinolyl)-[(2S)-5-vinylquinuclidin-2-yl]methanol
State
State

Halofantrine is typically found as a solid at room temperature.

Melting point (Celsius)
207.00
Melting point (Kelvin)
480.15
Boiling point (Celsius)
556.60
Boiling point (Kelvin)
829.80
General information
Molecular weight
503.58g/mol
Molar mass
503.5810g/mol
Density
1.2380g/cm3
Appearence

Halofantrine is a white to light beige powder. It may appear as crystalline solids under certain conditions.

Comment on solubility

Solubility of (6-methoxy-4-quinolyl)-[(2S)-5-vinylquinuclidin-2-yl]methanol

The solubility of a chemical compound is a crucial property that affects its application and usability in various fields. For the compound (6-methoxy-4-quinolyl)-[(2S)-5-vinylquinuclidin-2-yl]methanol, understanding its solubility can be quite complex, as it depends on multiple factors:

  • Polarity: Compounds with polar functional groups tend to be more soluble in polar solvents. The presence of the hydroxyl (-OH) group in this compound suggests potential for enhanced solubility in water.
  • Hydrogen Bonding: The -OH group can participate in hydrogen bonding, which often increases solubility in aqueous solutions.
  • Molecular Structure: The quinoline and quinuclidine moieties may introduce hydrophobic regions that could limit solubility in water while enhancing solubility in organic solvents.
  • pH Dependency: The solubility may also vary with pH changes, particularly if the compound can ionize in solution.

In summary, while one might expect (6-methoxy-4-quinolyl)-[(2S)-5-vinylquinuclidin-2-yl]methanol to possess some degree of solubility due to its hydroxyl group, the overall solubility profile is likely to be a balance between its polar and non-polar characteristics. Thus, experiments would be essential to determine the precise solubility behavior in various solvents.

Interesting facts

Interesting Facts about (6-methoxy-4-quinolyl)-[(2S)-5-vinylquinuclidin-2-yl]methanol

(6-methoxy-4-quinolyl)-[(2S)-5-vinylquinuclidin-2-yl]methanol, often referred to in research fields, is a compound that possesses intriguing characteristics and applications in the world of medicinal chemistry. Here are some compelling points to consider:

  • Pharmaceutical Potential: This compound is notable for its potential use in drug development. Its structure allows for interactions with various biological targets, making it a candidate for further exploration in therapeutic applications.
  • Quinolines in Chemistry: The quinoline backbone found in this compound is significant for its analogues that exhibit a wide range of biological activities, including antimalarial and antibacterial properties. Quinolines have long been a focus in medicinal chemistry.
  • Chirality Matters: The presence of the (2S) configuration highlights the importance of stereochemistry in pharmacology. The biological activity of compounds can vary greatly depending on their chiral nature, influencing how they interact with specific receptors in the body.
  • Research Insights: Studies involving this compound could provide insights into the mechanism of action for various biological processes, particularly in areas related to neurology and pain management, given the quinuclidine component's influence on neurotransmitter dynamics.
  • Creative Formulation: Scientists are fascinated by the possibility of combining this compound with other herbal or synthetic agents to create multifunctional drugs that target more than one disease at a time, which could be a revolutionary step in treatment approaches.

In summary, (6-methoxy-4-quinolyl)-[(2S)-5-vinylquinuclidin-2-yl]methanol is more than just a molecule; it represents the intersection of organic chemistry and medicinal science, where creativity and research converge to push the boundaries of health and disease treatment.

Synonyms
SCHEMBL20971893
HMS3749M11
NCGC00163142-01
NCGC00163142-02