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Tacrine Hydrobromide

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Identification
Molecular formula
C20H25BrN2O1
CAS number
204512-57-0
IUPAC name
(6-methoxy-4-quinolyl)-(5-vinylquinuclidin-2-yl)methanol;hydrobromide
State
State

This compound is typically in a solid state at room temperature.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
438.35g/mol
Molar mass
438.3520g/mol
Density
1.5000g/cm3
Appearence

Tacrine hydrobromide appears as a white crystalline powder.

Comment on solubility

Solubility of (6-methoxy-4-quinolyl)-(5-vinylquinuclidin-2-yl)methanol hydrobromide

The solubility of the compound (6-methoxy-4-quinolyl)-(5-vinylquinuclidin-2-yl)methanol hydrobromide is influenced by several factors, including its chemical structure and the presence of hydrobromide salt. Generally, salts tend to enhance solubility in aqueous solutions. Here are some key points regarding the solubility of this compound:

  • Hydrophilicity vs. Hydrophobicity: The presence of the hydrobromide component typically contributes to increased solubility in polar solvents, such as water.
  • Structural Considerations: The molecular structure, which includes both quinuclidine and quinoline derivatives, suggests that solubility may also be affected by the configuration and orientation of the functional groups.
  • Solvent Interactions: Polar solvents are likely to facilitate dissolution due to favorable interactions with ionic and polar portions of the molecule.
  • Temperature Dependency: Like many organic compounds, solubility may vary with temperature, often increasing as the temperature rises.

In conclusion, while (6-methoxy-4-quinolyl)-(5-vinylquinuclidin-2-yl)methanol hydrobromide is expected to exhibit good solubility in polar solvents, precise solubility data can be influenced by various factors such as concentration, temperature, and specific ionic interactions.

Interesting facts

Interesting Facts about (6-methoxy-4-quinolyl)-(5-vinylquinuclidin-2-yl)methanol; hydrobromide

The compound known as (6-methoxy-4-quinolyl)-(5-vinylquinuclidin-2-yl)methanol; hydrobromide is a fascinating subject of study due to its unique structure and potential biological applications. As a member of the quinoline family, it possesses intriguing properties that can be explored in various fields of research.

  • Diverse Applications: This compound is being investigated for its potential use in pharmaceuticals, particularly due to its structural resemblance to a range of biologically active molecules. Its derivatives may exhibit activities such as antimicrobial or antitumor effects.
  • Structural Nuances: The combination of the quinoline moiety and the quinuclidinyl fragment results in a compound that showcases a heterocyclic framework, which is a common feature in many drugs due to the importance of nitrogen atoms in influencing the molecule's reactivity and interaction with biological systems.
  • Synthetic Interest: The synthesis of this compound can be a challenging yet rewarding process. Chemists are often fascinated by the methodologies to create such compounds, which may involve multiple steps and the use of specialized reagents.
  • Research Potential: Scientists continue to study compounds like this one for their pharmacological properties. The interplay between the methanol group and the hydrobromide salt enhances solubility and stability, which is crucial for effective drug formulation.

As we delve deeper into the exploration of this compound, it's essential to appreciate the intricate balance between its chemical structure and potential applications. Further research could unveil even more about this exciting molecule, paving the way for innovative approaches in drug design and development.

Synonyms
MLS002638287
NSC12865
Quinine (Hydrobromide)
Cinchonan-9-ol, 6'-methoxy-, monohydrobromide, (8alpha,9R)- (9CI)
Quinine, hydrate
Quinine, hydrobromide, hydrate
SCHEMBL1694090
CHEMBL1881104
NSC-12865
SMR001547776
4-Quinolinemethanol, 6-methoxy-.alpha.-5-vinyl-2-quinuclidinyl hydrobromide
(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol,hydrobromide