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6-Methyluracil

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Identification
Molecular formula
C5H6N2O1
CAS number
626-48-2
IUPAC name
6-methyl-1H-pyrimidin-4-one
State
State

At room temperature, 6-Methyluracil is in a solid state. Due to its crystalline nature, it maintains a stable form under standard laboratory conditions.

Melting point (Celsius)
298.00
Melting point (Kelvin)
571.20
Boiling point (Celsius)
349.90
Boiling point (Kelvin)
623.00
General information
Molecular weight
126.11g/mol
Molar mass
126.1130g/mol
Density
1.2580g/cm3
Appearence

6-Methyluracil typically appears as a white crystalline solid. The powder form is fine and it has a faint characteristic odor. It is known for being relatively stable under standard conditions.

Comment on solubility

Solubility of 6-methyl-1H-pyrimidin-4-one

6-methyl-1H-pyrimidin-4-one is a compound whose solubility characteristics can significantly affect its applications in various fields, particularly in pharmaceuticals and research. The solubility of this compound is influenced by several factors:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents like water.
  • Hydrogen bonding: The ability to form hydrogen bonds can lead to better solubility in polar solvents, as molecules of 6-methyl-1H-pyrimidin-4-one may interact favorably with other polar molecules.
  • Temperature: Increasing the temperature often increases solubility, as it provides more energy for interactions between solute and solvent.
  • pH of the solution: Changes in pH can affect the ionization state of the compound, further influencing solubility in aqueous solutions.

In general, 6-methyl-1H-pyrimidin-4-one exhibits moderate solubility in common organic solvents such as methanol and ethanol, making it accessible for various experimental procedures. However, it is less soluble in non-polar solvents, which can limit its use in certain applications. Understanding these solubility aspects is crucial for optimizing concentration and dosage in practical applications.

To quote the rule of thumb for solubility: "Like dissolves like." This principle indicates that the solubility of 6-methyl-1H-pyrimidin-4-one will be higher in solvents with similar polarity to itself.

Interesting facts

Interesting Facts about 6-methyl-1H-pyrimidin-4-one

6-methyl-1H-pyrimidin-4-one is an intriguing compound that belongs to the class of pyrimidinones, which are important in various fields of chemistry, particularly medicinal chemistry. Here are some fascinating insights into this compound:

  • Biological Significance: Compounds related to pyrimidines are known for their roles in biological systems. For example, they are vital components of nucleotides and nucleic acids, which are essential for genetic information transfer in living organisms.
  • Pharmaceutical Applications: Many derivatives of pyrimidines, including 6-methyl-1H-pyrimidin-4-one, are studied for their potential therapeutic effects. They can exhibit a range of biological activities, including antimicrobial, antiviral, and anticancer properties.
  • Synthetic Versatility: The structure of 6-methyl-1H-pyrimidin-4-one allows for various synthetic modifications, making it a valuable precursor for the synthesis of more complex chemical entities. This versatility is crucial in drug development, where creating a myriad of derivatives is often necessary.
  • Mechanistic Studies: Scientists are interested in understanding the mechanisms of action of compounds like 6-methyl-1H-pyrimidin-4-one. This research can unveil new pathways for drug action, paving the way for innovative therapies in treating diseases.
  • Research Opportunities: As researchers delve deeper into the properties of this compound, potential new applications can be discovered. This makes it an exciting subject for students and scientists alike, who seek to explore its chemical behavior and biological interactions.

In conclusion, 6-methyl-1H-pyrimidin-4-one embodies a rich area of study where chemistry meets biology. Its potential implications in pharmacology and molecular biology continue to drive research and development, emphasizing the importance of compounds in advancing scientific knowledge and healthcare solutions.