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Kynurenic acid

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Identification
Molecular formula
C10H7NO3
CAS number
492-27-3
IUPAC name
6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid
State
State

At room temperature, kynurenic acid is in a solid state. It is typically found in a crystalline form and does not readily dissolve in water.

Melting point (Celsius)
340.00
Melting point (Kelvin)
613.00
Boiling point (Celsius)
684.00
Boiling point (Kelvin)
957.00
General information
Molecular weight
189.17g/mol
Molar mass
189.1730g/mol
Density
1.5290g/cm3
Appearence

Kynurenic acid appears as a white crystalline powder. It is relatively stable under normal conditions and has a creamy, white appearance when powdered.

Comment on solubility

Solubility of 6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid

6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid is an intriguing compound with notable solubility characteristics. Its solubility can be influenced by various factors, including:

  • Polarity: The presence of both the carboxylic acid group and the pyridine ring contributes to its polar nature, which generally increases its affinity for polar solvents.
  • pH Levels: Being a carboxylic acid, its solubility can significantly vary with pH. In acidic conditions, it can remain largely in its neutral form, while in alkaline conditions, it may ionize, leading to increased solubility in water.
  • Temperature: Typically, the solubility of organic compounds like this one increases with temperature, making heating an effective method to dissolve it in solvents.
  • Solvent Type: It displays enhanced solubility in polar protic solvents, such as water and ethanol, compared to non-polar solvents.

Overall, while it may have limited solubility in non-polar environments, its unique structure facilitates significant solubility in polar solvents under the right conditions. As one expert noted, "the interplay of functional groups and solvent polarity plays a crucial role in the solubility of such heterocyclic compounds." Thus, understanding the solubility of 6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid opens pathways for its practical applications in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid

6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid is a fascinating compound that belongs to the family of quinoline derivatives, which are known for their diverse biological activities. This compound has captured the attention of scientists due to its role in various fields, including pharmaceuticals and material science. Here are some interesting aspects of this compound:

  • Pharmacological Potential: Quinoline derivatives are often investigated for their potential as antimicrobial, anticancer, and anti-inflammatory agents. 6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid may exhibit similar biological properties.
  • Synthetic Applications: The compact structure of this compound enables it to serve as a valuable intermediate in the synthesis of more complex molecules. Researchers utilize it as a building block for developing novel compounds.
  • Role in Coordination Chemistry: This compound can form coordination complexes with metals, enhancing its utility in catalysis and materials science. These metal complexes can display improved physical properties that make them suitable for various applications.
  • Environmental Impact: Quinoline derivatives, including this compound, can serve as environmental indicators due to their stability and reactivity. They are often studied for their degradation products in ecological assessments.
  • Multiple Functionalities: The presence of both carboxylic acid and pyridine groups in its structure opens doors to a variety of reactions, showcasing the multifaceted nature of this compound in chemical research.

In conclusion, the compound 6-methyl-2-(3-pyridyl)quinoline-4-carboxylic acid exemplifies the rich potential of quinoline-based compounds. As research unfolds, its applications may lead to significant advancements in medicinal chemistry, material science, and environmental studies.

Synonyms
5110-02-1
6-methyl-2-(pyridin-3-yl)quinoline-4-carboxylic acid
CINCHONINIC ACID, 6-METHYL-2-(3-PYRIDYL)-
6-Methyl-2-(3-pyridyl)cinchoninic acid
DTXSID10199111
6-Methyl-2-(3-pyridyl)cinchoninsaeure [German]
Kyselin 6-metyl-2-(3-pyridyl)-cinchoninova [Czech]
6-Methyl-2-(3-pyridyl)cinchoninsaeure
Kyselin 6-metyl-2-(3-pyridyl)-cinchoninova
DTXCID40121602
857-685-1
6-methyl-2-pyridin-3-ylquinoline-4-carboxylic acid
MFCD00224693
Oprea1_550347
SCHEMBL18320684
ALBB-000752
BBL016701
STK430989
AKOS000148193
NCGC00343110-01
VS-05489
DB-028235
CS-0282031
EN300-71998
H21112
AB01334991-02
6-Methyl-2-(3-pyridinyl)-4-quinolinecarboxylic acid
6-methyl-2-(pyridin-3-yl)quinoline-4-carboxylicacid
Z228589410