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Coumarin-3-carboxylic acid

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Identification
Molecular formula
C11H8O4
CAS number
82-36-0
IUPAC name
6-methyl-2-oxo-chromene-3-carboxylic acid
State
State

At room temperature, Coumarin-3-carboxylic acid is in a solid state, typically as a crystalline powder.

Melting point (Celsius)
244.00
Melting point (Kelvin)
517.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
190.17g/mol
Molar mass
190.1650g/mol
Density
1.3510g/cm3
Appearence

Coumarin-3-carboxylic acid is a pale white crystalline solid.

Comment on solubility

Solubility of 6-Methyl-2-oxo-chromene-3-carboxylic Acid (C11H8O4)

The solubility of 6-methyl-2-oxo-chromene-3-carboxylic acid showcases some interesting characteristics. This compound belongs to the class of chromene derivatives, which can greatly influence its solubility profile in various solvents.

Key factors influencing solubility:

  • Polarity: The presence of carboxylic acid functional groups (–COOH) significantly increases the polarity of the molecule, enhancing its ability to interact with polar solvents such as water.
  • Hydrogen bonding: The carboxylic acid group can form hydrogen bonds with water molecules, promoting solubility in aqueous solutions.
  • Alkyl group influence: The methyl group at the 6-position can introduce some hydrophobic character, which may limit solubility in highly polar solvents, but it can also improve solubility in organic solvents like ethanol or acetone.

In general, 6-methyl-2-oxo-chromene-3-carboxylic acid is expected to exhibit moderate solubility in water and higher solubility in organic solvents due to its structural features. It's crucial to remember that the specific solubility can also be affected by factors such as temperature and the presence of other solutes.

In summary, the solubility of this compound is shaped by its unique molecular structure, allowing it to effectively dissolve in both polar and nonpolar environments, making it versatile for various chemical applications.

Interesting facts

Exploring 6-Methyl-2-oxo-chromene-3-carboxylic Acid

6-Methyl-2-oxo-chromene-3-carboxylic acid is a fascinating compound with intriguing properties and applications in various fields, particularly in medicinal chemistry and organic synthesis. Here are some interesting facts about this compound:

  • Structural Significance: This compound features a chromene backbone, which is a valuable scaffold in organic chemistry. Its unique structure contributes to a variety of biological activities.
  • Biological Relevance: Compounds related to chromenes have demonstrated antioxidant, anti-inflammatory, and antimicrobial effects. This suggests that 6-methyl-2-oxo-chromene-3-carboxylic acid may have potential therapeutic uses.
  • Synthesis Versatility: The synthesis of this compound can be accomplished through various methods, often involving the condensation of simple starting materials. Its versatility makes it a subject of interest in synthetic organic chemistry.
  • Chemical Behavior: The presence of both a ketone and carboxylic acid functional group in its structure allows the compound to participate in a range of chemical reactions, including esterification and amidation, enhancing its utility in chemical processes.
  • Research Potential: Ongoing research into derivatives of this compound continues to reveal new applications and modifications that can enhance its properties, opening doors to novel compounds with even greater efficacy.

In summary, 6-methyl-2-oxo-chromene-3-carboxylic acid is not just a simple compound but a potential key player in the development of new pharmaceutical agents and valuable chemical reactions. Its rich chemical framework allows for the exploration of additional derivatives that can impact various scientific domains.

Synonyms
10242-13-4
6-methyl-2-oxo-2H-chromene-3-carboxylic acid
6-methyl-2-oxochromene-3-carboxylic acid
2H-1-BENZOPYRAN-3-CARBOXYLIC ACID, 6-METHYL-2-OXO-
6-Methyl-2-oxo-2H-1-benzopyran-3-carboxylic acid
CHEMBL577123
2-Oxo-6-methyl-2H-1-benzopyran-3-carboxylic acid
MFCD01662452
6-methyl-2-oxidanylidene-chromene-3-carboxylic acid
BRN 0172386
5-18-08-00343 (Beilstein Handbook Reference)
SCHEMBL2808135
DTXSID00145066
FJICLQQBBFWGMZ-UHFFFAOYSA-N
HMS1622M11
BDBM50303488
SBB077427
AKOS002679479
PD182973
SY301814
6-methyl-2-oxo-2H-chromene-3-carboxylicacid
VU0511228-1
F3165-0705
LFW
SH7
SH8