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6-Methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid

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Identification
Molecular formula
C15H16O4
CAS number
87923-35-5
IUPAC name
6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid
State
State

Under standard conditions, 6-Methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid is a solid. It is typically handled as a powdered or crystalline substance in laboratory settings. The compound's stability and reactivity may vary depending on environmental factors such as temperature and humidity.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.15
Boiling point (Celsius)
354.00
Boiling point (Kelvin)
627.15
General information
Molecular weight
272.30g/mol
Molar mass
272.2950g/mol
Density
1.2130g/cm3
Appearence

6-Methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid typically appears as a solid crystalline substance. The texture and color may vary depending on the specific physical sample and any impurities present. The compound is generally stable under standard laboratory conditions but should be stored in a cool, dry place to maintain its integrity.

Comment on solubility

Solubility of 6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid

The solubility of 6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid can be influenced by several factors due to its complex molecular structure. Here are some key points that highlight its solubility characteristics:

  • Polar vs. Non-polar Solvents: This compound is likely to exhibit variable solubility in polar and non-polar solvents. Generally, compounds with carboxylic acid functional groups demonstrate increased solubility in polar solvents, such as water.
  • Hydrogen Bonding: The presence of the carboxylic acid group can facilitate hydrogen bonding, enhancing solubility in water and alcohols.
  • Hydrophobic Regions: The benzofuran moiety contributes hydrophobic characteristics, which might limit its solubility in strictly polar environments.
  • Temperature Effects: Like many organic compounds, the solubility may increase with temperature due to the increased kinetic energy facilitating interactions with solvent molecules.

In essence, while the solubility of 6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid in water is essential for many applications, its hydrophobic characteristics brought on by the benzofuran component could lead to limited solubility. As such, understanding its solubility profile necessitates careful consideration of both environmental conditions and the solvents in question.

Interesting facts

Interesting Facts about 6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid

6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid is a fascinating compound that belongs to the class of benzofuran derivatives. This chemical has garnered interest in various fields of research due to its unique structure and potential biological activities.

Structural Characteristics

This compound is distinguished by:

  • Benzofuran Core: The benzofuran moiety provides a stable aromatic structure that is essential for biological activity.
  • Methyl Substitution: The presence of a methyl group enhances its lipophilicity, influencing how the compound interacts with biological membranes.
  • Carboxylic Acid Group: This functional group plays a crucial role in the reactivity and solubility of the compound, making it a versatile entity in synthetic chemistry.

Biological Relevance

Research indicates that compounds like 6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid may possess various bioactivities, such as:

  • Antioxidant properties: This can aid in neutralizing free radicals in biological systems.
  • Anti-inflammatory effects: Potentially significant for therapeutic applications in various inflammatory diseases.
  • Antimicrobial activity: Compounds with similar structures have shown effectiveness against certain pathogens.

Applications in Chemistry

The potential applications of this compound include:

  • As a precursor in the synthesis of complex organic molecules.
  • In the development of pharmaceutical agents, particularly in creating compounds with enhanced efficacy.
  • In research settings that explore the structure-activity relationships of bioactive compounds.

Overall, 6-methyl-5-(2-methylenebutanoyl)benzofuran-2-carboxylic acid stands out as an intriguing compound in organic and medicinal chemistry, offering numerous opportunities for exploration and application in scientific research. As noted by scientists, "The complexity of natural products often leads to the discovery of novel and useful chemical entities."

Synonyms
FURACRINIC ACID
23580-33-8
acido furacrinico
acide furacrinique
UNII-TO15Q907ZS
Furacrinic acid [INN:BAN]
TO15Q907ZS
FURACRINIC ACID [INN]
DTXSID40178217
6-Methyl-5-(2-methylenebutyryl)-2-benzofurancarboxylic acid
acidum furacrinicum
RefChem:141727
DTXCID70100708
48-674
6-methyl-5-(2-methylidenebutanoyl)-1-benzofuran-2-carboxylic acid
CHEMBL2106339
SCHEMBL11008170
NS00121049
Q27290051