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Tetrabenazine hydrochloride

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Identification
Molecular formula
C19H27NO3Cl
CAS number
313-44-0
IUPAC name
6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
State
State

At room temperature, Tetrabenazine hydrochloride is a solid.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.00
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.00
General information
Molecular weight
317.82g/mol
Molar mass
317.8180g/mol
Density
1.2350g/cm3
Appearence

Tetrabenazine hydrochloride appears as a white to slightly yellowish solid.

Comment on solubility

Solubility of 6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

The solubility of 6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride is influenced by several factors due to its complex structure. This compound is a quaternary ammonium salt, which generally suggests notable solubility characteristics. Here are some key points to consider:

  • Polar Solvent Compatibility: Due to the presence of the chloride anion and the dioxolo moiety, this compound is likely to exhibit good solubility in polar solvents like water and alcohols.
  • Hydrophilic Nature: The ionic nature of the chloride component typically enhances its interaction with water molecules, contributing to its overall hydrophilicity.
  • Hydrophobic Moieties: The isoquinoline structure may introduce some hydrophobic characteristics, which could affect solubility in entirely nonpolar solvents.
  • Temperature Effects: Solubility can be temperature-dependent; thus, increased temperatures might improve solubility in certain solvents.

In conclusion, while the exact solubility value may vary based on experimental conditions and solvent choice, this compound's ionic nature most often ensures that it is more soluble in polar environments compared to nonpolar ones. As is often stated, *“Like dissolves like,”* emphasizing the importance of polarity in determining solubility outcomes.

Interesting facts

Interesting Facts about 6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

This intriguing compound, known for its complex structure, contains a dihydroisoquinoline framework that has captured the interest of chemists and pharmacologists alike. Here are some noteworthy points:

  • Structural Diversity: The compound features a unique tetrahydro-dioxole moiety fused with an isoquinoline, which enhances its potential reactivity and interaction with biological systems.
  • Pharmaceutical Potential: Compounds of this class are often studied for their possible therapeutic applications, particularly in neurology and psychiatry. There’s ongoing research into their effects on neurotransmitter systems.
  • Electrochemical Activities: The presence of an ionic chloride species suggests that this compound may exhibit interesting electrochemical behavior, making it a candidate for studies in material science and electrochemistry.
  • Natural Products Inspiration: Many compounds resembling the structure of this compound have been isolated from natural sources. This highlights the importance of natural product chemistry in drug discovery.
  • Complex Synthesis: The synthesis of 6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride is quite challenging and often requires multiple reaction steps, showcasing the ingenuity of synthetic chemists.

The study of such compounds not only expands our understanding of chemical behavior but also opens doors to innovative medicinal applications. As stated by a notable chemist, "The beauty of chemistry lies in its complexity and diversity, which fuels our desire to explore and innovate."

Further research could unveil even more about this compound's properties and its potential role in various scientific fields. With its multifaceted nature, 6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride remains a captivating subject in the realm of chemical science.

Synonyms
Deoxyhydrastinine hydrochloride
9OAD694X77
1,3-DIOXOLO(4,5-g)ISOQUINOLINE, 5,6,7,8-TETRAHYDRO-6-METHYL-, HYDROCHLORIDE
Hydrohydrastinine, hydrochloride
EINECS 227-802-5
NSC 113006
UNII-9OAD694X77
N-Methyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinoline, hydrochloride