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Isatin

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Identification
Molecular formula
C8H5NO2
CAS number
91-56-5
IUPAC name
6-methylindoline-2,3-dione
State
State
Isatin is a solid at room temperature.
Melting point (Celsius)
200.00
Melting point (Kelvin)
473.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
147.14g/mol
Molar mass
147.1410g/mol
Density
1.5261g/cm3
Appearence

Isatin is a yellow-orange to reddish-brown crystalline solid. It can appear in the form of fine crystals or powder. The compound is known for its distinct color and is used as a dye intermediate.

Comment on solubility

Solubility of 6-methylindoline-2,3-dione

6-methylindoline-2,3-dione, a compound known for its distinctive structure, displays intriguing solubility characteristics.

In terms of solubility, this compound tends to be:

  • Soluble in organic solvents: 6-methylindoline-2,3-dione is generally soluble in non-polar to moderately polar organic solvents, which is typical for many organic compounds.
  • Poorly soluble in water: This compound shows limited solubility in water due to its relatively hydrophobic indoline structure, which hinders interactions with water molecules.

As with many organic compounds, the solubility can be influenced by various factors, including:

  1. Temperature: Increased temperature may enhance solubility in organic solvents.
  2. pH levels: The solubility might vary if the compound is in an acidic or basic environment, affecting potential ionization.
  3. Presence of other solutes: The interaction with other chemicals can create complex solubilities.

In conclusion, while 6-methylindoline-2,3-dione has a clear solubility profile in organic solvents, its limited solubility in water reflects the compound's unique structure, making it a fascinating subject for further chemical exploration.

Interesting facts

Interesting Facts about 6-Methylindoline-2,3-dione

6-Methylindoline-2,3-dione, commonly known as a derivative of indoline, is a fascinating compound in the realm of organic chemistry. This particular molecule exhibits a range of intriguing properties and applications, making it a subject of interest for both researchers and students alike.

Key Characteristics

  • Versatile Derivative: The presence of a methyl group at the 6-position significantly influences the electronic and steric properties of the indoline framework, opening up potential pathways for synthesis and chemical reactivity.
  • Biological Relevance: Some studies suggest that compounds like 6-methylindoline-2,3-dione may exhibit biological activity, which can be explored for potential pharmacological applications.
  • Fluorescence: Compounds in the indoline family often have interesting photophysical properties, including fluorescence, which can be harnessed in various sensors and imaging applications.

Applications and Implications

  1. Synthetic Intermediates: 6-Methylindoline-2,3-dione serves as a useful intermediate in the synthesis of dyes, pharmaceuticals, and other useful compounds.
  2. Research Tool: Its distinct structure makes it useful in the study of reaction mechanisms in organic synthesis.
  3. Potential Therapeutics: Researchers are exploring its importance in developing new drugs due to its unique structure and potential biological activity.

As a scientist studying this compound, one might reflect on the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." Exploring the myriad applications of 6-methylindoline-2,3-dione may spark the next big innovation in synthetic chemistry or pharmacology!

Synonyms
6-Methylisatin
1128-47-8
6-methyl-1H-indole-2,3-dione
6-Methylindoline-2,3-dione
1H-Indole-2,3-dione, 6-methyl-
INDOLE-2,3-DIONE, 6-METHYL-
MFCD01718832
BRN 0129704
6-methyl isatin
6-Methylindole-2,3-dione
SCHEMBL4192180
DTXSID20920897
ALBB-014228
STK213103
AKOS005174371
FM35245
SB64264
2-Hydroxy-6-methyl-3H-indol-3-one #
6-Methyl isatinic anhydride, AldrichCPR
AS-19982
SY016308
DB-023846
CS-0137579
5-21-11-00178 (Beilstein Handbook Reference)
Z274364524