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2-Amino-6-methylpyridine

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Identification
Molecular formula
C6H8N2
CAS number
1979-45-1
IUPAC name
6-methylpyridin-2-amine
State
State

At room temperature, 2-Amino-6-methylpyridine is typically in a solid state, appearing as crystalline powder.

Melting point (Celsius)
41.00
Melting point (Kelvin)
314.15
Boiling point (Celsius)
233.00
Boiling point (Kelvin)
506.15
General information
Molecular weight
108.15g/mol
Molar mass
108.1460g/mol
Density
1.0260g/cm3
Appearence

2-Amino-6-methylpyridine typically appears as a pale yellow solid or crystalline powder that might have a slight amine-like odor. It is usually found in its pure form for laboratory or industrial use.

Comment on solubility

Solubility of 6-methylpyridin-2-amine

6-methylpyridin-2-amine, with its unique structural properties, displays some interesting characteristics regarding its solubility. Here are a few key points to consider:

  • Polarity: Due to the presence of the amino group (-NH2) and the methyl group in the pyridine ring, 6-methylpyridin-2-amine is relatively polar.
  • Solvent Compatibility: It is generally soluble in polar solvents such as water and alcohol, but may have limited solubility in non-polar solvents.
  • Temperature Effects: The solubility can increase with temperature, making it easier for this compound to dissolve at higher temperatures.
  • Concentration and pH: The solubility can also be influenced by the pH of the solution. In acidic environments, the amino group can become protonated, which may enhance solubility.

In conclusion, the solubility of 6-methylpyridin-2-amine can be influenced by several factors, including its polarity, the type of solvent used, temperature, and the pH of the solution. Always consider these aspects when working with this compound to achieve optimal solubility.

Interesting facts

Interesting Facts About 6-methylpyridin-2-amine

6-methylpyridin-2-amine is a fascinating compound that combines the structural attributes of pyridine with a methyl group and an amine functional group. This unique combination leads to a variety of interesting properties and applications:

  • Structure and Isomerism: The compound features a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom. The location of the methyl group, as well as the amine group at specific positions, demonstrates the importance of isomeric forms in organic chemistry.
  • Biological Activity: Compounds like 6-methylpyridin-2-amine often demonstrate significant biological activity. For instance, analogs of this compound can be explored in the context of pharmacology for their potential therapeutic effects.
  • Industrial Relevance: This compound can act as an intermediate in the synthesis of other complex molecules, making it valuable in drug development and the production of various fine chemicals.
  • Research Applications: The study of 6-methylpyridin-2-amine and its derivatives is relevant in the field of combinatorial chemistry, where chemists seek to create diverse libraries of compounds for screening in biological assays.
  • Functionalization Potential: The presence of the amino group allows for further functionalization reactions, paving the way for the introduction of various side chains that can enhance biological activity or modify properties.

In summary, 6-methylpyridin-2-amine is not only an intriguing structural entity but also one with practical implications in diverse fields such as medicinal chemistry, materials science, and organic synthesis. Its ability to serve as a foundational building block in various chemical reactions underscores the beauty and utility of organic molecules in scientific research.

Synonyms
2-Amino-6-methylpyridine
6-methylpyridin-2-amine
2-Amino-6-picoline
2-Pyridinamine, 6-methyl-
6-Methyl-2-pyridinamine
2-Picoline, 6-amino-
6-Methyl-2-pyridylamine
6-Amino-2-methylpyridine
6-Methyl-2-aminopyridine
PYRIDINE, 2-AMINO-6-METHYL-
NSC 6971
NSC 1488
UNII-35ANN6MRBM
35ANN6MRBM
2-amino-6-methyl pyridine
EINECS 217-360-1
BRN 0107048
DTXSID0044860
AI3-24112
NSC-1488
NSC-6971
DTXCID8024860
5-22-09-00210 (Beilstein Handbook Reference)
AMINO-6-METHYLPYRIDINE, 2-
2-Picoline, 6-amino-(8CI)
inchi=1/c6h8n2/c1-5-3-2-4-6(7)8-5/h2-4h,1h3,(h2,7,8
quxlcyfnvnnrbe-uhfffaoysa-n
1824-81-3
6-Amino-2-picoline
MFCD00006331
2-amino-6-methyl-pyridine
6-Methyl-pyridin-2-ylamine
CHEMBL61591
WLN: T6NJ BZ F1
2-?Amino-?6-?methylpyridine
6-methylpyridin-2-ylamine
6-aminopicoline
6-Amino picoline
2-amino 6 picoline
2-amino-6methylpyridine
2-amino-6-methylpyridin
6-amino-2-methyl-pyridine
6-methyl-2-amino pyridine
2-Amino-6-methylpyridine (2-Amino-6-picoline)
6-methyl-pyridin-2-yl-amine
SCHEMBL102316
6-methylpyridin-2(1H)-imine
NSC1488
NSC6971
2-Amino-6-methylpyridine, 98%
BCP22085
Tox21_300667
BDBM50091794
RB1111
STK301586
STL453503
AKOS000119669
AB00717
AC-7554
CS-W018543
GS-6756
NCGC00248134-01
NCGC00254575-01
CAS-1824-81-3
DB-023785
A0403
NS00026005
EN300-19899
Q27256454
F1995-0201
Z104476000
71M