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6-Methyl-3-pyridinol

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Identification
Molecular formula
C6H7NO
CAS number
1121-11-9
IUPAC name
6-methylpyridin-3-ol
State
State

At room temperature, 6-Methyl-3-pyridinol is typically found in a solid state as it has a relatively high melting point.

Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
109.13g/mol
Molar mass
109.1260g/mol
Density
1.0545g/cm3
Appearence

6-Methyl-3-pyridinol typically appears as a crystalline solid. The compound consists of white or off-white crystals. Their appearance may vary depending on the level of purity and specific form of the sample.

Comment on solubility

Solubility of 6-methylpyridin-3-ol

6-methylpyridin-3-ol, a derivative of pyridine, exhibits some interesting solubility characteristics. Understanding the solubility of this compound is crucial for its practical applications in various chemical processes. Here are some notable points regarding its solubility:

  • Polar Nature: Due to the presence of the hydroxyl group (-OH) attached to the pyridine ring, 6-methylpyridin-3-ol is relatively polar, which enhances its solubility in polar solvents.
  • Solvent Compatibility: This compound is generally soluble in water and various organic solvents such as alcohols and acetone, making it versatile in different chemical environments.
  • Hydrogen Bonding: The hydroxyl group facilitates hydrogen bonding with water molecules, increasing its solubility in aqueous solutions.
  • Temperature Dependency: Like many organic compounds, the solubility of 6-methylpyridin-3-ol can increase with temperature, demonstrating the influence of thermal energy on solubility.

In summary, 6-methylpyridin-3-ol's solubility is significantly influenced by its polar characteristics, solvent interactions, and the temperature of the solution. Its compatibility with various solvents makes it a compound of interest in both research and industrial applications.

Interesting facts

6-Methylpyridin-3-ol: An Insight into its Unique Properties

6-Methylpyridin-3-ol is a fascinating compound that features a pyridine ring, a six-membered aromatic ring containing one nitrogen atom. This compound holds importance in various fields, particularly in organic chemistry and pharmaceuticals. Here are some intriguing facts about 6-methylpyridin-3-ol:

  • Structural Significance: The placement of the hydroxyl group (-OH) and the methyl group (-CH₃) at the 3rd and 6th positions of the pyridine ring grants this compound unique physicochemical properties which can influence its reactivity and interaction with biological systems.
  • Biological Activity: Compounds within the pyridine family, including 6-methylpyridin-3-ol, are often studied for their potential biological activities. Some of these compounds exhibit antibacterial, antifungal, and anti-inflammatory properties, making them essential in medicinal chemistry.
  • Applications in Synthesis: 6-Methylpyridin-3-ol is invaluable in synthetic organic chemistry. It can act as a building block for more complex molecules, participating in a variety of reactions such as methylation and hydrogenation.
  • Research Frontier: Continuous research is being conducted to explore the roles this compound can play in drug development, especially for conditions that affect the central nervous system due to its ability to cross the blood-brain barrier.
  • Flavor and Fragrance: Interestingly, pyridine derivatives can also be found in flavor compounds and fragrances due to their aromatic properties, lending unique scents and tastes to various products.

In summary, 6-methylpyridin-3-ol is more than just a simple compound; it is an essential player in the realm of organic chemistry with numerous applications and research potential. As scientists delve deeper into its properties, we uncover more about its contributions to both synthetic chemistry and biological systems.

Synonyms
5-Hydroxy-2-methylpyridine
1121-78-4
6-Methylpyridin-3-ol
2-Methyl-5-hydroxypyridine
3-HYDROXY-6-METHYLPYRIDINE
6-Methyl-3-pyridinol
3-Pyridinol, 6-methyl-
6-Methyl-3-hydroxypyridine
5-Hydroxy-2-picoline
2-methyl-5-pyridinol
UKE16JP1JR
EINECS 214-337-8
NSC 27963
BRN 0107077
DTXSID4051580
NSC-27963
3-PYRIDOL, 6-METHYL-
DTXCID8030132
DHLUJPLHLZJUBW-UHFFFAOYSA-
5-21-02-00139 (Beilstein Handbook Reference)
HYDROXY-6-METHYLPYRIDINE, 3-
inchi=1/c6h7no/c1-5-2-3-6(8)4-7-5/h2-4,8h,1h3
MFCD00006339
2-methyl-5-hydroxy pyridine
UNII-UKE16JP1JR
2-methyl-5-hydroxy-pyridine
6-Methyl-3-hydroxypyridine; 6-Methyl-3-pyridinol; NSC 27963
5-hydroxypicoline
6-Methyl-3-pyridol; 2-Methyl-5-hydroxypyridine; 2-Methyl-5-pyridinol; 3-Hydroxy-6-methylpyridine; 5-Hydroxy-2-methylpyridine; 5-Hydroxy-2-picoline
6-Methyl-pyridin-3-ol
6-methyl-pyridine-3-ol
2-methyl-5hydroxypyridine
5-hydroxy-2-methylpridine
3-hydroxy-6-methyl-pyridine
5-hydroxy-2-methyl pyridine
5-hydroxy-2-methyl-pyridine
6-methyl-3-hydroxy-pyridine
SCHEMBL104940
5-Hydroxy-2-methylpyridine (5-Hydroxy-2-picoline)
CHEMBL134979
5-Hydroxy-2-methylpyridine, 99%
NSC27963
STR03888
Tox21_304013
CL0058
AKOS007930884
AC-5086
CS-W004681
FH35512
PB30543
NCGC00357226-01
BP-10108
SY007644
CAS-1121-78-4
H0763
NS00023606
EN300-55469
AC-907/25014124
Q27291117
F0001-0268
Z838078132