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6-Nitrobenzothiazol-2-amine

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Identification
Molecular formula
C7H5N3O2S
CAS number
5335-84-0
IUPAC name
6-nitro-1,3-benzothiazol-2-amine
State
State

At room temperature, 6-Nitrobenzothiazol-2-amine is in a solid state. It forms crystalline structures that are stable under standard conditions.

Melting point (Celsius)
107.00
Melting point (Kelvin)
380.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
196.21g/mol
Molar mass
196.2060g/mol
Density
1.5420g/cm3
Appearence

6-Nitrobenzothiazol-2-amine typically appears as a yellow crystalline powder. Its vibrant hue is indicative of the presence of the nitro group in the compound, which is common for nitroaromatic compounds.

Comment on solubility

Solubility of 6-nitro-1,3-benzothiazol-2-amine

6-nitro-1,3-benzothiazol-2-amine is a relatively complex organic compound that displays interesting solubility characteristics. The solubility of this compound can be influenced by various factors, including its molecular structure and the polarity of the solvents used. Here are some key points regarding its solubility:

  • Solvent Dependence: This compound tends to be more soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol while showing limited solubility in polar protic solvents like water.
  • Hydrophobic Interactions: Due to the presence of the nitro group and thiazole ring, there are notable hydrophobic interactions that may hinder solubility in aqueous environments.
  • pH Sensitivity: The solubility may also vary with pH levels; in acidic or basic conditions, the ionization of functional groups can enhance solubility.
  • Temperature Influence: As with many organic compounds, increasing the temperature can facilitate dissolution, making heated solvent systems effective for achieving higher solubility.

In summary, while 6-nitro-1,3-benzothiazol-2-amine is not particularly soluble in water, its solubility can be optimized using organic solvents, varying pH, and temperature adjustments. Understanding these solubility characteristics is crucial for its application in chemical research and industry.

Interesting facts

Interesting Facts about 6-Nitro-1,3-benzothiazol-2-amine

6-Nitro-1,3-benzothiazol-2-amine is a fascinating compound with a variety of applications in chemistry and biology. Here are some intriguing aspects of this compound:

  • Structure and Composition: This compound features a nitro group (-NO2) attached to a benzothiazole ring, which is itself a bicyclic structure incorporating both nitrogen and sulfur atoms. This unique structural makeup contributes to its interesting chemical properties.
  • Chemical Reactivity: The presence of the nitro group significantly alters the reactivity of the benzothiazole framework, making it more suitable for various reactions, including nucleophilic substitutions. This property is particularly advantageous in synthetic organic chemistry.
  • Application in Research: Compounds like 6-nitro-1,3-benzothiazol-2-amine have shown potential in drug development, especially in the creation of anti-cancer agents and antimicrobial substances. This highlights its significance in medicinal chemistry.
  • Environmental Importance: The study of nitro compounds, including this one, is essential in environmental chemistry, as their behavior and degradation pathways in biological systems are key to understanding their potential toxicity and ecological impact.
  • Potential as a Fluorescent Probe: Some derivatives of benzothiazole compounds have been explored as fluorescent probes due to their ability to emit light upon excitation, opening avenues for biological imaging and detection applications.

In summary, 6-nitro-1,3-benzothiazol-2-amine is not just a simple chemical entity but a compound rich with potential in various scientific fields. Its applications span from synthetic chemistry to medicinal uses, showcasing the importance of studying such compounds in-depth.

Synonyms
2-AMINO-6-NITROBENZOTHIAZOLE
6-Nitro-1,3-benzothiazol-2-amine
2-Benzothiazolamine, 6-nitro-
6-Nitrobenzothiazol-2-amine
6-Nitro-2-aminobenzothiazole
Benzothiazole, 2-amino-6-nitro-
6-Nitro-2-benzothiazolamine
NSC 62341
CCRIS 1391
EINECS 228-513-7
NSC 10794
NSC 62980
BRN 0177844
DTXSID3024491
UNII-4321510DG9
NSC-10794
NSC-62341
NSC-62980
DTXCID304491
4321510DG9
4-27-00-04876 (Beilstein Handbook Reference)
6-NITRO-2-BENZOTHIAZOLEAMINE
AMINO-6-NITROBENZOTHIAZOLE, 2-
Benzothiazole, 2-amino-6-nitro-(8CI)
gpnavojcqiekqf-uhfffaoysa-n
inchi=1/c7h5n3o2s/c8-7-9-5-2-1-4(10(11)12)3-6(5)13-7/h1-3h,(h2,8,9
6285-57-0
6-nitrobenzo[d]thiazol-2-amine
MFCD00005786
6-Nitro-benzothiazol-2-ylamine
CHEMBL318275
2-Amino-6-nitro benzothiazole
NCGC00091632-02
Maybridge1_005516
2-amino-6-nitrobenzthiazole
NCIOpen2_000006
NCIOpen2_000201
DivK1c_001804
SCHEMBL334808
2-amino-6-nitro-benzothiazole
HMS557C16
BCP26738
NSC10794
NSC62341
NSC62980
Tox21_400044
BDBM50335098
STK353543
AKOS000111205
6-Nitro-1,3-benzothiazol-2-amine #
2-Amino-6-nitrobenzothiazole, >=97%
CDS1_000764
NCGC00091632-01
NCGC00091632-03
AC-11336
AS-14458
SY049419
CAS-6285-57-0
DB-001002
A1221
NS00035197
EN300-20235
A15715
F30827
Q27258594
F0015-0759
Z104477436