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6-nitro-3,1-benzoxazine-2,4-dione

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Identification
Molecular formula
C8H4N2O5
CAS number
825-75-8
IUPAC name
6-nitro-1H-3,1-benzoxazine-2,4-dione
State
State

At room temperature, 6-nitro-3,1-benzoxazine-2,4-dione is typically found as a solid. It is not volatile and maintains its solid state under ambient conditions.

Melting point (Celsius)
142.50
Melting point (Kelvin)
415.60
Boiling point (Celsius)
518.15
Boiling point (Kelvin)
791.30
General information
Molecular weight
214.13g/mol
Molar mass
214.1270g/mol
Density
1.5300g/cm3
Appearence

The compound typically appears as a yellow crystalline solid. It may also exist in a powder form depending on the level of refinement and the exact conditions under which it is observed.

Comment on solubility

Solubility of 6-nitro-1H-3,1-benzoxazine-2,4-dione

The solubility of 6-nitro-1H-3,1-benzoxazine-2,4-dione can be quite interesting given its unique chemical structure. This compound, often used in various chemical applications, exhibits particular solubility characteristics:

  • Polar Solvents: It tends to be more soluble in polar solvents such as water and ethanol, which may be attributed to the presence of nitro groups that enhance hydrogen bonding.
  • Apolar Solvents: Conversely, the solubility in apolar solvents like hexane and toluene is typically low due to the insufficient interactions between the compound and the solvent molecules.
  • pH Dependency: The solubility may also vary with pH; acidic or alkaline conditions can significantly affect its ionization and, consequently, its solubility.

In conclusion, while 6-nitro-1H-3,1-benzoxazine-2,4-dione shows promising solubility in certain conditions, understanding its complete solubility profile requires further investigation into specific solvent interactions and environmental factors.

Interesting facts

Interesting Facts about 6-nitro-1H-3,1-benzoxazine-2,4-dione

6-nitro-1H-3,1-benzoxazine-2,4-dione, often referred to as a member of the benzoxazine family, exhibits fascinating characteristics that have been the subject of extensive research. This compound is significant for its diverse applications in various fields, particularly in medicinal chemistry and material science. Here are some engaging insights:

  • Versatile Intermediate: It serves as a key intermediate in organic synthesis, leading to the development of novel compounds with potential therapeutic applications.
  • Pharmacological Potential: Research has indicated that derivatives of benzoxazine can exhibit anti-cancer, anti-inflammatory, and anti-microbial properties, making them promising candidates for drug development.
  • Nitro Group Influence: The presence of the nitro group in its structure can significantly influence the compound's electronic and chemical properties, allowing for fine-tuning in synthetic pathways.
  • Polymer Chemistry: Benzoxazines are studied for their role in creating thermoset polymers, which are important in producing strong, heat-resistant materials used in various industrial applications.
  • Biomolecules: The interaction of compounds like 6-nitro-1H-3,1-benzoxazine-2,4-dione with biological systems opens avenues for understanding complex biomolecular pathways.

The study of benzoxazine derivatives is a vivid example of how a seemingly simple compound can lead to significant advancements in both chemistry and practical applications. This compound stands out as a versatile platform that continues to inspire a wealth of scientific inquiry.

As a dedicated researcher or chemistry student, exploring such compounds can enhance your understanding of the intricate connections between molecular structure and biological activity, as well as the profound impact of chemistry on real-world issues.

Synonyms
5-Nitroisatoic anhydride
4693-02-1
2H-3,1-BENZOXAZINE-2,4(1H)-DIONE, 6-NITRO-
6-Nitroisatoic anhydride
6-Nitro-2H-3,1-benzoxazine-2,4(1H)-dione
EINECS 225-151-1
NSC 73615
BRN 0219188
DTXSID7063558
4-27-00-03332 (Beilstein Handbook Reference)
DTXCID8040519
225-151-1
6-Nitro-1H-benzo[d][1,3]oxazine-2,4-dione
5-nitro-isatoic anhydride
6-nitro-1H-3,1-benzoxazine-2,4-dione
5-Nitroisatoic anhydride, tech.
MFCD00023891
NSC-73615
5-Nitro-isatoicanhydride
NCIOpen2_003931
SCHEMBL870661
6-nitro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione
E3HJ2SF662
WWUBAHSWMPFIQZ-UHFFFAOYSA-
6-Nitro-2H-3,4(1H)-dione
NSC73615
2H-3,4(1H)-dione, 6-nitro-
AKOS003620666
CS-W015232
FN67112
AC-19357
AS-39072
6-nitrobenzo[d][1,3]oxazine-2,4-dione
DB-031746
NS00031646
EN300-385165
2H-3,1-Benzoxazine-2,4(1H)-dione,5-nitro-
Z1094719210
4-nitro-8-oxa-10-azabicyclo[4.4.0]deca-2,4,11-triene-7,9-dione
InChI=1/C8H4N2O5/c11-7-5-3-4(10(13)14)1-2-6(5)9-8(12)15-7/h1-3H,(H,9,12)