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6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one

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Identification
Molecular formula
C14H8N2O4
CAS number
14687-81-3
IUPAC name
6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one
State
State

At room temperature, this compound is in a solid state. It is typically found in powder or crystalline form, making it easy to handle in laboratory settings.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
340.50
Boiling point (Kelvin)
613.70
General information
Molecular weight
280.24g/mol
Molar mass
280.2410g/mol
Density
1.3500g/cm3
Appearence

This compound appears as a yellow crystalline solid. The color is indicative of the nitro group, which often imparts a yellow hue to organic compounds due to the presence of azo chromophores.

Comment on solubility

Solubility of 6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one

The solubility of 6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one can be influenced by several factors. This compound is characterized by a complex molecular structure, which typically affects its ability to dissolve in various solvents.

Key Factors Affecting Solubility:

  • Polarity: The presence of nitro groups (-NO2) can increase polar character, potentially improving solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds may enhance solubility in protic solvents.
  • Temperature: Increased temperature often leads to greater solubility, but the specific effect for this compound may vary.
  • pH of the Solution: The solubility can be affected by the acidity or basicity of the medium.

In practice, 6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one is often found to have limited solubility in water but might demonstrate better solubility in organic solvents such as ethanol or DMSO. This behavior makes it crucial to select appropriate solvents for its applications.

In conclusion, understanding the solubility properties of this compound is essential for its effective utilization in various chemical processes and formulations.

Interesting facts

Exploring 6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one

6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one is a unique chemical compound that belongs to the class of benzoxazins, which are known for their diverse biological and chemical properties. Here are some fascinating insights into this compound:

  • Biological Significance: Compounds in the benzoxazine family often exhibit interesting biological activities, including antimicrobial and anticancer properties. The presence of a nitro group in this compound might enhance its reactivity and make it a candidate for further research in medicinal chemistry.
  • Applications: Due to its specific structural features, this compound may find applications in various fields, such as:
    • Pharmaceutical development
    • Agricultural products
    • Organic synthesis
  • Research Potential: The insights into the mechanism of action of benzoxazines, including this compound, could lead to breakthroughs in drug discovery. Researchers are often drawn to compounds with nitro substituents due to their potential to participate in various chemical reactions.
  • Structure-Activity Relationship: The specific arrangement of atoms in 6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one may influence its pharmacological profile. The study of such relationships is crucial in the fields of medicinal chemistry and drug design.

The exploration of compounds like 6-nitro-3-phenyl-2H-1,3-benzoxazin-4-one not only broadens our understanding of organic chemistry but also paves the way for innovative applications in medicinal and industrial chemistry.

Synonyms
20979-01-5
BRN 1590486
4H-1,3-BENZOXAZIN-4-ONE, 2,3-DIHYDRO-6-NITRO-3-PHENYL-
DTXSID20175183
2,3-Dihydro-6-nitro-3-phenyl-4H-1,3-benzoxazin-4-one
RefChem:297030
DTXCID9097674