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6-Phenyl-1,2,3,4-tetrahydroisoquinoline

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Identification
Molecular formula
C15H15N
CAS number
22974-33-0
IUPAC name
6-phenyl-1,2,3,4-tetrahydroisoquinoline
State
State

At room temperature, 6-Phenyl-1,2,3,4-tetrahydroisoquinoline is a solid.

Melting point (Celsius)
50.00
Melting point (Kelvin)
323.15
Boiling point (Celsius)
368.00
Boiling point (Kelvin)
641.15
General information
Molecular weight
221.29g/mol
Molar mass
221.2940g/mol
Density
1.0200g/cm3
Appearence

6-Phenyl-1,2,3,4-tetrahydroisoquinoline is typically a crystalline solid. Its appearance can be characterized by its white to off-white color, depending on the purity and specific synthesis pathway used.

Comment on solubility

Solubility of 6-phenyl-1,2,3,4-tetrahydroisoquinoline

6-phenyl-1,2,3,4-tetrahydroisoquinoline is a fascinating compound when it comes to its solubility characteristics. Generally, the solubility of this compound can be influenced by several factors, including:

  • Polarity: The presence of the phenyl group contributes to a non-polar characteristic, which often results in low solubility in polar solvents such as water.
  • Solvent Interaction: It tends to be more soluble in non-polar organic solvents like chloroform, ethanol, or hexane.
  • Temperature Dependency: Like many organic compounds, its solubility can increase with higher temperatures, making it important to consider temperature during experimental procedures.

In summary, while 6-phenyl-1,2,3,4-tetrahydroisoquinoline is not highly soluble in water, it displays a noteworthy affinity for organic solvents. As a rule of thumb, “like dissolves like” applies, meaning that this compound will favor non-polar environments for dissolution.

Interesting facts

Interesting Facts about 6-phenyl-1,2,3,4-tetrahydroisoquinoline

6-phenyl-1,2,3,4-tetrahydroisoquinoline is a fascinating compound that belongs to the class of tetrahydroisoquinolines, which are known for their complex structure and diverse biological activities. Here are some intriguing details about this compound:

  • Structural Diversity: The tetrahydroisoquinoline framework allows for a wide variety of substitutions, which can significantly influence the chemical and biological properties of the compound.
  • Pharmacological Importance: Compounds related to 6-phenyl-1,2,3,4-tetrahydroisoquinoline have been studied for their potential use in treating various neurological conditions. They may show promise as:
    • Antidepressants
    • Analgesics
    • Neuroprotective agents
  • Synthesis Insight: The synthesis of this compound typically involves multi-step processes which can include:
    • Rearrangement reactions
    • Cyclization steps
    • Functional group modifications
  • Natural Occurrence: Compounds with similar structures are often found in various natural products, indicating their evolutionary significance in nature.
  • Research Spotlight: Ongoing studies focus on the structure-activity relationship, helping to tailor the compound for specific therapeutic effects.

In summary, 6-phenyl-1,2,3,4-tetrahydroisoquinoline exemplifies the intersection of chemistry and medicine, showcasing how structural nuances can lead to profound impacts in the field of pharmaceuticals. The potential applications and ongoing research make it an exciting subject for both scientists and students alike.

Synonyms
6-phenyl-1,2,3,4-tetrahydroisoquinoline
24464-39-9
SCHEMBL5254986
SCHEMBL5254989
SCHEMBL6347388
NZZKRRROOQVMFN-UHFFFAOYSA-N
AKOS013709864
DA-07745
6-phenyl-1,2,3,4-tetrahydro-isoquinoline
EN300-1477330