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Lasofoxifene

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Identification
Molecular formula
C28H31NO2
CAS number
154212-61-0
IUPAC name
6-phenyl-5-[4-[2-(1-piperidyl)ethoxy]phenyl]-7,8-dihydronaphthalen-2-ol
State
State

At room temperature, lasofoxifene exists in a solid state.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.10
Boiling point (Celsius)
536.10
Boiling point (Kelvin)
809.30
General information
Molecular weight
405.56g/mol
Molar mass
405.5400g/mol
Density
1.2868g/cm3
Appearence

Lasofoxifene is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 6-phenyl-5-[4-[2-(1-piperidyl)ethoxy]phenyl]-7,8-dihydronaphthalen-2-ol

The solubility of 6-phenyl-5-[4-[2-(1-piperidyl)ethoxy]phenyl]-7,8-dihydronaphthalen-2-ol, a complex organic compound, can be influenced by several factors. Here are key points to consider:

  • Polarity: The incorporation of the piperidyl and ethoxy groups adds polar characteristics to the molecule, which may enhance solubility in polar solvents like water or alcohols.
  • Hydrophobic regions: The naphthalene component and phenyl substitutions contribute to hydrophobic properties, potentially limiting solubility in polar solvents.
  • Temperature: Generally, solubility tends to increase with temperature; thus, warming the solvent could improve the dissolution of this compound.
  • pH Levels: The ionization of hydroxyl groups in varying pH environments can significantly affect solubility; shifts towards more alkaline conditions may enhance solubility through deprotonation.
  • Concentration: Solubility will vary based on the concentration of the compound in the solvent; higher concentrations may lead to saturation quickly.

In summary, the solubility of 6-phenyl-5-[4-[2-(1-piperidyl)ethoxy]phenyl]-7,8-dihydronaphthalen-2-ol is not straightforward and will largely depend on these multifaceted factors. Understanding these elements can provide greater insight into this compound's behavior in different environments.

Interesting facts

Interesting Facts about 6-phenyl-5-[4-[2-(1-piperidyl)ethoxy]phenyl]-7,8-dihydronaphthalen-2-ol

This compound belongs to a fascinating class of chemical entities that have garnered attention for their potential applications in medicinal chemistry. Here are some compelling points to consider:

  • Pharmacological Potential: Compounds like this one are often investigated for their role as evolving pharmaceutical agents. They may possess unique properties that could lead to the development of new treatments for various diseases.
  • Structural Complexity: The intricate structure, characterized by both naphthalene and aromatic phenyl groups, showcases the compound's potential to interact with biological systems in a multifaceted way. This complexity can enhance selectivity and efficacy.
  • Piperidine Linkage: The presence of the piperidyl moiety suggests that this compound might exhibit interesting neuropharmacological properties. Piperidine derivatives are known for their diverse biological activities, which may be explored further in drug design.
  • Research Interest: Due to their complexity, compounds like this have become a particular focus of research initiatives aimed at understanding their pharmacokinetics and toxicity. Investigating their mechanisms of action can unlock new pathways for therapeutic interventions.
  • Part of a Larger Family: This compound can be viewed as part of a larger class of phenolic compounds that are recognized for their antioxidant properties and potential health benefits. Such attributes make them appealing in both clinical and nutritional settings.

Overall, the exploration of 6-phenyl-5-[4-[2-(1-piperidyl)ethoxy]phenyl]-7,8-dihydronaphthalen-2-ol offers a glimpse into the intricate world of organic compounds and their potential transformative impact on science and medicine.