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Isorhynchophylline

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Identification
Molecular formula
C22H28N2O3
CAS number
51084-96-1
IUPAC name
6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol
State
State

Isorhynchophylline is in a solid state under standard conditions, displaying a crystalline structure.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
384.47g/mol
Molar mass
384.4540g/mol
Density
1.2800g/cm3
Appearence

Isorhynchophylline appears as a solid crystalline powder. It typically has a yellowish color and appears quite homogeneous under normal lighting.

Comment on solubility

Solubility of 6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol

The solubility of 6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol (C22H28N2O3) can be influenced by several factors, making it an intriguing compound in terms of its dissolution characteristics. Key points to consider regarding its solubility include:

  • Polarity: The presence of hydroxyl (–OH) groups in the structure suggests that this compound may exhibit some degree of hydrophilicity, potentially aiding its solubility in polar solvents.
  • Hydrophobic regions: With a large hydrocarbon chain and a complex aromatic structure, the molecule also possesses hydrophobic characteristics, which might limit its solubility in water but enhance solubility in organic solvents.
  • Effect of pH: The solubility could vary with pH due to the ionization of the functional groups, which might be more soluble in basic conditions compared to acidic ones.
  • Solvent selection: Therefore, it is important to explore a range of solvents. It may be more soluble in solvents such as ethanol or dimethyl sulfoxide (DMSO) compared to water.

As stated in solubility theory, "like dissolves like," which suggests that the choice of solvent is critical when considering the solubility of this compound. Therefore, targeted experiments should be considered to ascertain the most effective solvents and conditions for optimal solubility.

Interesting facts

Interesting Facts about 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol

6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol is a fascinating compound with a complex structure that brings several notable points to light. Here are some interesting aspects from the perspective of a chemical scientist or a chemistry student:

  • Diverse Applications: This compound is a member of the dibenzoquinoline family and has potential applications in fields such as medicinal chemistry and pharmaceutical development. Its structure suggests it may possess valuable biological activity, warranting further investigation.
  • Synthetic Challenges: Synthesizing compounds like this one can be challenging due to their intricate multi-ring structures. The creation of the propyl group and the positioning of hydroxyl (-OH) groups demand a thoughtful approach to reaction conditions and reagents.
  • Structure-Activity Relationship: The specific arrangement of functional groups in this compound is crucial. Studying how alterations in the structure affect biological activity can lead to the design of more effective drugs.
  • Natural Products: Compounds with similar structures have been isolated from natural sources. This raises intriguing questions about their role in ecology and natural selection.
  • Research Frontier: The compound is a subject of ongoing research due to its potential pharmacological properties, especially in treating conditions related to the central nervous system. Investigating its effects on neuronal function could reveal important insights.

As one delves deeper into the chemistry and potential uses of 6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol, it becomes clear how exploring such compounds can contribute to various branches of science, including organic chemistry, pharmacology, and materials science. The complexity and potential utility of such structures are what make them a captivating area of study!

Synonyms
HUA9N4Y9JB
6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol
2-OH-Npa, (+/-)-
UNII-HUA9N4Y9JB
2,10,11-trihydroxy-n-propylnoraporphine
2,10,11-Trihydroxy-n-propylnoraporphine, (+/-)-
586391-22-2
5,6,6a,7-Tetrahydro-6-propyl-4H-dibenzo(de,g)quinoline-2,10,11-triol
4H-Dibenzo(de,g)quinoline-2,10,11-triol, 5,6,6a,7-tetrahydro-6-propyl-
SCHEMBL1325958
NCGC00162160-01
NCGC00162160-02
PD092282
(-)2,10,11-trihydroxy-N-n-propylnoraporphine