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Mianserin hydrochloride

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Identification
Molecular formula
C18H21ClN2
CAS number
21535-47-7
IUPAC name
6-pyrrolidin-1-ium-1-yl-7H-benzo[d][1,3]benzodiazepine;chloride
State
State

At room temperature, mianserin hydrochloride is typically in a solid state in the form of a crystalline powder.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
92.00
Boiling point (Kelvin)
365.15
General information
Molecular weight
334.88g/mol
Molar mass
334.8820g/mol
Density
1.4428g/cm3
Appearence

The compound appears as a white to off-white crystalline powder. It is typically available in a purified form for use in scientific research or pharmaceutical applications.

Comment on solubility

Solubility of 6-pyrrolidin-1-ium-1-yl-7H-benzo[d][1,3]benzodiazepine; chloride

The solubility of 6-pyrrolidin-1-ium-1-yl-7H-benzo[d][1,3]benzodiazepine; chloride can be somewhat intricate due to its chemical structure. Generally, the solubility of organic compounds such as this one is influenced by several key factors:

  • Polarity: The presence of polar groups in the molecule enhances solubility in polar solvents like water.
  • Ionic interactions: As a chloride salt, this compound may demonstrate good solubility in aqueous solutions due to its ionic nature.
  • Hydrophobic regions: The benzodiazepine ring systems can create hydrophobic interactions, which may influence solubility in organic solvents.

In essence, one may observe that:

  • If tested in polar solvents, the compound likely exhibits a moderate to high solubility.
  • Conversely, solubility in non-polar solvents may be low due to its structure.

To summarize, the solubility behavior of this specific compound is largely contingent upon the solvent used; thus, performing solubility tests in various media is crucial for a comprehensive understanding.

Interesting facts

Interesting Facts about 6-pyrrolidin-1-ium-1-yl-7H-benzo[d][1,3]benzodiazepine;chloride

6-pyrrolidin-1-ium-1-yl-7H-benzo[d][1,3]benzodiazepine;chloride is a remarkable compound belonging to the benzodiazepine family, which is widely studied for its medicinal properties. Here are some intriguing aspects that highlight its significance:

  • Medicinal Relevance: This compound is often analyzed for its potential effects on the central nervous system, particularly its anxiolytic and sedative properties. Benzodiazepines are known for their ability to enhance the effects of the neurotransmitter GABA, making them useful in treating conditions like anxiety and insomnia.
  • Chemical Structure: The unique benzo[d][1,3]benzodiazepine core coupled with the pyrrolidin-1-ium group provides a rich platform for studying structure-activity relationships. This allows scientists to modify structural components to optimize efficacy and minimize side effects.
  • Electrostatic Interactions: The presence of the quaternary ammonium structure (pyrrolidin-1-ium) leads to interesting interactions with biomolecules, potentially influencing pharmacokinetics and binding affinity. This property can be exploited to design targeted drug delivery systems.
  • Research Applications: Due to its interaction with neurotransmitter systems, this compound is a valuable subject for research in pharmacology and neuroscience, potentially paving the way for new therapeutic agents that can more effectively manage neurological disorders.
  • Potential for Side Effects: While benzodiazepines are highly effective, they also carry a risk of dependence and side effects, which scientists continuously investigate. Understanding the nuances of compounds like this one helps in better drug design to mitigate such concerns.

In conclusion, 6-pyrrolidin-1-ium-1-yl-7H-benzo[d][1,3]benzodiazepine;chloride is not only a chemical entity of interest due to its structural features but also plays a critical role in medicinal chemistry, opening pathways for potential therapeutic applications and advancements in neuroscience research. The ongoing exploration of its characteristics keeps it at the forefront of scientific inquiry.

Synonyms
6-(1-Pyrrolidinyl)-5H-dibenzo(d,f)(1,3)diazepine hydrochloride
5H-DIBENZO(d,f)(1,3)DIAZEPINE, 6-(1-PYRROLIDINYL)-, MONOHYDROCHLORIDE
2849-08-3