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Pirenzepine

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Identification
Molecular formula
C19H21N3O2
CAS number
28797-61-7
IUPAC name
6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine
State
State

At room temperature, Pirenzepine is typically found in a solid state.

Melting point (Celsius)
202.00
Melting point (Kelvin)
475.15
Boiling point (Celsius)
992.78
Boiling point (Kelvin)
1 265.93
General information
Molecular weight
351.40g/mol
Molar mass
351.8600g/mol
Density
1.4900g/cm3
Appearence

Pirenzepine typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine

The solubility of 6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine can be influenced by several factors, making it an interesting compound to study in this regard.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents like water.
  • Hydrophobic Interactions: Conversely, the hydrophobic nature of the benzodiazepine framework may limit solubility in aqueous environments.
  • pH Levels: Changes in pH can affect the ionization state of the compound, thereby altering its solubility.
  • Temperature: Typically, increasing temperature enhances solubility for many solid compounds.

Although specific solubility data for this compound might be limited, it is essential to consider that compounds in the benzodiazepine family often exhibit moderate to low solubility in water, but may dissolve in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).

As stated, “Solubility is key in determining the bioavailability of pharmacologically active compounds.” Therefore, understanding the solubility characteristics of 6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine is crucial for its application in medicinal chemistry and formulation development.

Interesting facts

Interesting Facts about 6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine

6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine, a complex chemical compound, belongs to the benzodiazepine family, known for their psychoactive properties. Here are some fascinating insights into this particular compound:

  • Psychoactive Effects: As a member of the benzodiazepine class, this compound may exhibit various effects on the central nervous system, including anxiolytic (anxiety-reducing), sedative, and hypnotic properties.
  • Structure-Activity Relationship: The unique structure of 6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine contributes to its binding affinity with GABAA receptors, which play a crucial role in mediating inhibitory neurotransmission.
  • Potential Therapeutic Uses: This compound and similar benzodiazepines are often explored for their potential use in treating conditions such as anxiety disorders, insomnia, and even epilepsy due to their ability to enhance the calming effects of GABA.
  • Chemical Synthesis: The synthesis of such compounds involves advanced organic chemistry techniques, often requiring multiple steps of reactions to construct the aromatic rings and functional groups effectively.
  • Research and Development: Ongoing studies are being conducted to assess the safety, efficacy, and potential side effects of derivatives of this compound, highlighting its importance in pharmacology and medicinal chemistry.

In summary, 6-pyrrolidin-1-yl-7H-benzo[d][1,3]benzodiazepine is not just a simple chemical compound; it embodies a wealth of research opportunities and therapeutic potential that continue to intrigue scientists and students alike.