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Coumarin 6

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Identification
Molecular formula
C20H25ClN2O4
CAS number
38215-36-0
IUPAC name
6,7-bis[2-(diethylamino)ethoxy]-4-methyl-chromen-2-one
State
State

At room temperature, Coumarin 6 is a solid. Its crystalline form allows it to be handled as a powder, making it suitable for various applications, including dye and fluorescence studies. The material is stable under normal conditions but should be protected from excessive light and moisture to preserve its integrity.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
435.20
Boiling point (Kelvin)
708.35
General information
Molecular weight
450.55g/mol
Molar mass
450.5490g/mol
Density
1.0670g/cm3
Appearence

Coumarin 6 typically presents as a yellow-green crystalline powder. It is fluorescent in nature, often used as a tracer dye due to its vibrant color under UV light. The solid state is finely particulate, and care should be taken to avoid inhalation of the dust.

Comment on solubility

Solubility of 6,7-bis[2-(diethylamino)ethoxy]-4-methyl-chromen-2-one

The solubility of 6,7-bis[2-(diethylamino)ethoxy]-4-methyl-chromen-2-one, a complex organic compound, can vary significantly based on several factors. Here are some key insights:

  • Solvent type: This compound generally exhibits better solubility in organic solvents such as dichloromethane, ethyl acetate, and ethanol due to its hydrophobic aromatic structure.
  • Temperature effects: Increased temperature often leads to enhanced solubility for many organic compounds, including this one, allowing for more effective dissolution.
  • pH dependency: The presence of various functional groups in the structure can make solubility sensitive to pH changes. In aqueous solutions, altering the pH can affect ionization and thus change solubility.
  • Concentration gradients: Higher concentrations of this compound in a suitable solvent may lead to saturation, beyond which solubility traits become more critical.

In conclusion, the solubility characteristics of 6,7-bis[2-(diethylamino)ethoxy]-4-methyl-chromen-2-one make it an interesting compound to study, particularly in organic synthesis and formulation contexts. Understanding the interactions with various solvents can enhance its utility in diverse applications.

Interesting facts

Interesting Facts about 6,7-bis[2-(diethylamino)ethoxy]-4-methyl-chromen-2-one

This intriguing compound belongs to the class of chromenones, which are known for their diverse biological properties and applications. Chromenones, derived from natural products, have gained attention in medicinal chemistry for their potential as therapeutic agents.

Biological Significance

  • Antioxidant Activity: Some derivatives of chromenone have shown antioxidant properties, which can help in combating oxidative stress in biological systems.
  • Anticancer Potential: Certain compounds in this class have been explored for their efficacy against various cancer cell lines, offering hope for new cancer therapies.
  • Antimicrobial Properties: Research suggests that chromenones can exhibit antibacterial and antifungal activity, making them candidates for pharmaceuticals.

Synthetic Importance

The structure of this compound, with its unique diethylamino groups and ethoxy chains, highlights its potential for modification. This opens avenues for:

  • Leverage different substitution to enhance biological activity.
  • Develop novel compounds for specific therapeutic targets.

Potential Applications

Due to its multiple functionalities, this chromenone derivative can be a valuable molecule for:

  • Drug Development: Exploring its effects as a lead compound in drug design.
  • Fluorescence Studies: Utilized in fluorescence microscopy due to the presence of chromophoric systems.

In addition to its medicinal usage, compounds like this one provide a fascinating glimpse into the interdisciplinary nature of chemistry, bridging gaps between synthetic chemistry, pharmacology, and even materials science. The ongoing research in this field will likely reveal more surprising capabilities and applications, making it a truly exciting area of study for both chemists and biologists alike.

Synonyms
OXAMARIN
15301-80-1
Oxamarine
Oxamarinum
Oxamarina
Oxamarin [INN]
7M1L7AS5QJ
6,7-bis[2-(diethylamino)ethoxy]-4-methylchromen-2-one
6,7-Bis(2-(diethylamino)ethoxy)-4-methylcoumarin
2H-1-Benzopyran-2-one, 6,7-bis(2-(diethylamino)ethoxy)-4-methyl-
Ossamarina
Ossamarina [DCIT]
OXAMARIN [MI]
Oxamarine [INN-French]
Oxamarinum [INN-Latin]
Oxamarina [INN-Spanish]
UNII-7M1L7AS5QJ
SCHEMBL628427
orb1695786
CHEMBL2111036
DTXSID50165198
CHEBI:135614
QAA30180
AKOS040753399
NS00122789
6,7-Bis(2-diethylaminoethoxy)-4-methylcumarin
Q27268554