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Erythromycin A

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
[6,7-dihydroxy-8-(hydroxymethyl)-16-isopropenyl-4,18-dimethyl-5-oxo-14-phenyl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] 5-phenylpenta-2,4-dienoate
State
State

At room temperature, Erythromycin A is typically found in a solid state as a powder. Its stability in this state allows it storage and formulation into various pharmaceutical preparations. It is often packaged in dry form to be made into solutions or tablets depending on medical requirements.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
733.94g/mol
Molar mass
733.9380g/mol
Density
1.2400g/cm3
Appearence

Erythromycin A typically appears as a white or slightly yellow crystalline powder. It is known for its lack of odor and its bitter taste. Due to its crystalline nature, it may have a sheen or luster when viewed in bulk.

Comment on solubility

Solubility of the Compound

The solubility of [6,7-dihydroxy-8-(hydroxymethyl)-16-isopropenyl-4,18-dimethyl-5-oxo-14-phenyl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] 5-phenylpenta-2,4-dienoate (C37H67NO13) tends to present certain challenges due to its complex structure and high molecular weight. Understanding its solubility behavior is crucial for practical applications. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple hydroxyl groups suggests a degree of polarity, which can enhance solubility in polar solvents such as water.
  • Hydrophobic Regions: The presence of isopropenyl and phenyl groups may impede solubility in polar solvents, indicating a preference for non-polar or mildly polar organic solvents like ethanol or methanol.
  • Complex Interactions: The intricate cyclohexane structure may lead to unique intermolecular interactions that can affect solubility positively or negatively.

In summary, due to the conflicting influences of hydrophilic and hydrophobic components, the solubility of this compound is likely to be variable, necessitating careful evaluation in different solvent systems to determine its practical usability. As with many complex organic compounds, experimental solubility data would be beneficial to provide a definitive insight into its solubility characteristics.

Interesting facts

Interesting Facts about 6,7-dihydroxy-8-(hydroxymethyl)-16-isopropenyl-4,18-dimethyl-5-oxo-14-phenyl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl 5-phenylpenta-2,4-dienoate

This complex organic compound is fascinating both for its structure and its potential applications in various fields. Here are some key points that highlight its significance:

  • Structural Complexity: The intricate arrangement of multiple cyclic structures and functional groups in this compound demonstrates a high level of molecular complexity, contributing to its unique chemical properties.
  • Potential Therapeutic Uses: Compounds with similar structural motifs have been explored for their pharmacological properties. This compound might exhibit potential activity against various diseases, which warrants further investigation.
  • Natural Occurrence: Many molecules with such complex frameworks are often derived from natural sources. Understanding the biosynthetic pathways of compounds like this can lead to insights into medicinal chemistry and natural product synthesis.
  • Optical Activity: The presence of multiple chiral centers suggests that this compound may exist in various stereoisomeric forms, an aspect that must be carefully analyzed when considering its biological activity.
  • Applications in Material Science: Due to its robust framework, it could be useful in developing advanced materials, such as as polymer additives or in nanotechnology, where stability and unique properties are crucial.

As student chemists delve into the world of organic synthesis and compound characterization, compounds like this one reveal the beauty and complexity of chemistry, inviting curiosity and exploration.

In the words of famed chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Each complex molecule opens a door to new possibilities!

Synonyms
mezerein
34807-41-5
DTXSID50860510
Q905397
[6,7-Dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-5-oxo-14-phenyl-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] 5-phenylpenta-2,4-dienoate
5,5a-Dihydroxy-4a-(hydroxymethyl)-7,9-dimethyl-6-oxo-2-phenyl-10a-(prop-1-en-2-yl)-3a,3c,4a,5,5a,6,8a,9,10,10a-decahydro-2H,3bH-2,8b-epoxyoxireno[6,7]azuleno[5,4-e][1,3]benzodioxol-10-yl 5-phenylpenta-2,4-dienoate