Skip to main content

6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline

ADVERTISEMENT
Identification
Molecular formula
C12H15NO2
CAS number
18786-24-8
IUPAC name
6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline
State
State

At room temperature, 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline is in a crystalline solid state, indicating a stable and solid form suitable for laboratory handling and applications.

Melting point (Celsius)
36.00
Melting point (Kelvin)
309.15
Boiling point (Celsius)
223.00
Boiling point (Kelvin)
496.15
General information
Molecular weight
205.25g/mol
Molar mass
205.2520g/mol
Density
1.1292g/cm3
Appearence

6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline is typically presented as a crystalline solid when purified. It usually appears in white to off-white color.

Comment on solubility

Solubility of 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline

The solubility of 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline in various solvents can be quite intriguing due to its structural properties. This compound, as indicated by its complex molecular structure, presents unique solvation characteristics. Key points to consider include:

  • Organic Solvents: It tends to show appreciable solubility in many organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO).
  • Aqueous Solutions: Its solubility in water is relatively low, common for many organic compounds due to their hydrophobic regions.
  • Influencing Factors: Factors such as temperature and pH can significantly affect solubility, with increased temperature often enhancing solubility in organic solvents.

In summary, while 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline exhibits favorable solubility in polar organic solvents, its limited water solubility is not uncommon for compounds of this type. It is crucial to consider these properties when conducting experiments or formulating solutions with this compound.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline

This fascinating compound, 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline, is part of the isoquinoline family, which is renowned for its diverse biological activities. Here are some remarkable points about this compound:

  • Natural Occurrence: Isoquinolines are often found in nature, particularly in various plants and even in some marine organisms. They play critical roles in the biological systems of these organisms.
  • Medicinal Properties: Compounds related to isoquinolines exhibit a wide range of pharmacological activities. They are known for their potential in treating diseases such as:
    • Neurological disorders - some isoquinoline derivatives have shown promise in aiding conditions like Parkinson's disease.
    • Cancer - studies have indicated that certain isoquinoline compounds possess anti-cancer properties.
    • Anti-inflammatory effects - research suggests that some isoquinolines can help reduce inflammation.
  • Systematic Research: The analysis of compounds like 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline continues to be a rich field of study in medicinal chemistry, as researchers explore their potential as drug candidates.
  • Structural Insights: The unique structure of isoquinolines, featuring a bicyclic system and the presence of methoxy groups in this specific compound, often contributes to the enhanced biological activity by altering lipophilicity and receptor interactions.
  • Chirality and Activity: The chirality of isoquinolines can significantly influence their pharmacological effects. The right-handed or left-handed orientation of the compound might target different biological pathways.

In summary, 6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline not only captivates chemists with its intriguing structure but also with its impressive array of potential therapeutic properties. As research continues to unveil the mysteries of such compounds, the future of pharmaceuticals could indeed be bright!

Synonyms
4721-98-6
6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline
1-Methyl-6,7-dimethoxy-3,4-dihydroisoquinoline
CHEMBL291083
3,4-Dihydro-6,7-dimethoxy-1-methylisoquinoline
6,7-Dimethoxy-1-methyl-3,4-dihydro-isoquinoline
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-methyl-
Dehydrosalsolidine
MFCD00040276
Maybridge1_001068
Oprea1_325770
MLS001049069
SCHEMBL1148346
HMS544I12
VASUQTGZAPZKFK-UHFFFAOYSA-
DTXSID80197068
CHEBI:181377
HMS2268B08
BBL027945
BDBM50014656
NSC144726
STK801970
AKOS000268865
CCG-233943
DS-6978
NSC 144726
NSC-144726
RTE3_000047
NCGC00246204-01
SMR000386907
DB-019262
CS-0061398
PK04_181304
1-methyl-3,4-dihydro-6,7-dimethoxyisoquinoline
AE-848/02267015
6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline #
BRD-K55034919-001-08-1
InChI=1/C12H15NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h6-7H,4-5H2,1-3H3