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6,7-Dimethoxy-1-methylisoquinoline

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Identification
Molecular formula
C12H13NO2
CAS number
16202-80-3
IUPAC name
6,7-dimethoxy-1-methyl-isoquinoline
State
State

At room temperature, 6,7-Dimethoxy-1-methylisoquinoline is typically a solid.

Melting point (Celsius)
69.00
Melting point (Kelvin)
342.15
Boiling point (Celsius)
297.00
Boiling point (Kelvin)
570.15
General information
Molecular weight
203.25g/mol
Molar mass
203.2470g/mol
Density
1.1160g/cm3
Appearence

6,7-Dimethoxy-1-methylisoquinoline is typically a solid substance. It may appear as a crystalline powder with a pale color, often yellowish or off-white.

Comment on solubility

Solubility of 6,7-dimethoxy-1-methyl-isoquinoline

The solubility of 6,7-dimethoxy-1-methyl-isoquinoline is an intriguing subject due to its complex molecular structure. Here are some key aspects to consider:

  • Polarity: The presence of methoxy groups can enhance solubility in polar solvents, while the isoquinoline ring may lead to reduced solubility in nonpolar environments.
  • Solvent Choices: This compound is likely to show better solubility in:
    • Alcohols (e.g., ethanol, methanol)
    • Aqueous solutions under certain pH conditions
    • Dimethyl sulfoxide (DMSO)
  • Temperature Effects: Increasing temperature can frequently improve the solubility of organic compounds, making it essential to consider thermal conditions when examining solubility.
  • Concentration Variability: Higher concentrations of 6,7-dimethoxy-1-methyl-isoquinoline may lead to precipitation in less polar solvents due to solubility limits.

In conclusion, the solubility of 6,7-dimethoxy-1-methyl-isoquinoline is influenced by factors such as polarity, solvent choice, temperature, and concentration. Understanding these elements is crucial for practical applications in pharmaceuticals and organic synthesis.

Interesting facts

Interesting Facts about 6,7-dimethoxy-1-methyl-isoquinoline

6,7-dimethoxy-1-methyl-isoquinoline is a fascinating compound found within the isoquinoline family, which is well-known for its rich diversity in structure and biological activity. Here are some intriguing aspects that a scientist or chemistry student might find engaging:

  • Isoquinoline Derivatives: Isoquinolines are notable for their prominent presence in various natural products and pharmaceuticals. The unique structure of this compound allows it to interact with biological systems in intriguing ways, making it a subject of interest in medicinal chemistry.
  • Potential Biological Activities: Compounds containing isoquinoline structures have been researched for their antioxidant, antimicrobial, and anticancer properties. This particular compound has been investigated for its potential therapeutic applications, leading to ongoing interest in its biological effects.
  • Dimethoxy Groups: The two methoxy groups present in the molecule are not merely decorative; they significantly impact the compound's electronic properties and pharmacokinetics. Such substitutions can enhance solubility and modulate activity levels, which are critical in drug design and formulation.
  • Synthesis and Characterization: The synthesis of 6,7-dimethoxy-1-methyl-isoquinoline can involve various organic reactions, showcasing the versatility and creativity of chemists. It often requires techniques such as condensation reactions or the use of specific catalysts to achieve the desired product.
  • Research Significance: As studies continue, the compound has the potential to reveal new insights into neuropharmacology and cognitive enhancement, due to isoquinolines' similar structure to neurotransmitters. Such connections could unlock further understanding of neurological disorders.

In conclusion, 6,7-dimethoxy-1-methyl-isoquinoline exemplifies the beauty and complexity of organic compounds. As researchers continue to explore its properties and effects, the potential for significant discoveries remains vast in the realms of both chemistry and biology.

Synonyms
Isosalsolidine
6,7-Dimethoxy-1-methylisoquinoline
Nigellimine
4594-02-9
ISOQUINOLINE, 6,7-DIMETHOXY-1-METHYL-
4722-12-7
1-methyl-6,7-dimethoxyisoquinoline
BRN 0148112
SCHEMBL3974591
DTXSID70196661
CHEBI:196004
VBMZFACBWDZUSM-UHFFFAOYSA-N
1-Methyl-6,7-dimethoxyisochinolin
AKOS024015288
6,7-Dimethoxy-1-methylisoquinoline, 9CI
DB-333309
5-21-05-00151 (Beilstein Handbook Reference)
AE-641/01100050
InChI=1/C12H15NO2/c1-8-10-7-12(15-3)11(14-2)6-9(10)4-5-13-8/h5-8H,4H2,1-3H