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Tetrahydropapaverine hydrochloride

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Identification
Molecular formula
C13H20ClNO2
CAS number
1484-55-5
IUPAC name
6,7-dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
State
State

At room temperature, this compound is typically in a solid state due to its crystalline form.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.00
Boiling point (Celsius)
348.00
Boiling point (Kelvin)
621.00
General information
Molecular weight
283.80g/mol
Molar mass
283.8010g/mol
Density
1.2900g/cm3
Appearence

The compound typically appears as a white or off-white crystalline powder. It is known for its crystalline nature, which can vary in shape and size under microscopic examination.

Comment on solubility

Solubility of 6,7-Dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; Chloride

The solubility of 6,7-dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride is influenced by several factors, which can determine how this compound interacts in various environments.

  • Polarity: As a quaternary ammonium salt, this compound tends to exhibit high polarity, often resulting in good solubility in polar solvents such as water.
  • Temperature: Generally, increased temperature can enhance solubility. For quaternary ammonium salts, elevated temperatures often facilitate the dissolution process.
  • pH Levels: The solubility may vary with changes in pH. It is vital to consider the pH of the solvent, as it can significantly influence ionization and solubility.
  • Interaction with other compounds: The presence of other ions or molecules may either enhance or impede solubility through complexation or salt formation.

In conclusion, while 6,7-dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride is generally soluble in polar solvents like water, the exact solubility will depend on the surrounding conditions. Understanding these factors is crucial for utilizing this compound effectively in various applications.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium Chloride

The compound 6,7-dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride is a fascinating example of a tetrahydroisoquinoline derivative, which are known for their structural diversity and biological significance.

Key Highlights:

  • Bioactivity: Compounds of this class have been studied for their potential pharmacological activities, including neuroprotective, antitumor, and analgesic effects.
  • Chemical Structure: The tetrahydroisoquinoline framework is of particular interest due to its ability to interact with various biological targets.
  • Dimethoxy Groups: The presence of methoxy groups at the 6 and 7 positions can significantly affect the compound's lipophilicity and reactivity. This can influence the compound's overall pharmacokinetic properties.
  • Synthesis: These complex organic molecules are often synthesized through multi-step reactions that allow for careful control of stereochemistry and function, presenting rich opportunities for organic chemists.

Due to its unique structure, this compound opens avenues for research into novel therapeutic agents. As one scholar noted, "The study of isoquinolines not only sheds light on organic synthesis but also on potential new drugs." Such insights into the compound's activity and interactions make it a valuable entity in medicinal chemistry.

In summary, 6,7-dimethoxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride showcases the interplay between structure and function in organic compounds, highlighting the importance of interdisciplinary research that bridges chemistry with pharmacology.