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Tetrahydropapaverine chloride

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Identification
Molecular formula
C11H16ClNO2
CAS number
56153-03-4
IUPAC name
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
State
State

At room temperature, tetrahydropapaverine chloride is generally in the solid state. It is comprised of crystalline particles typical of alkaloid hydrochloride salts. Such compounds are commonly solicited as stable powders for research and industrial use.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.00
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.00
General information
Molecular weight
275.78g/mol
Molar mass
275.7790g/mol
Density
1.2750g/cm3
Appearence

The compound typically appears as a white or off-white crystalline solid. It may also be available as a crystalline powder. The compound has a noticeable crystalline structure and is visually similar to other alkaloid salts.

Comment on solubility

Solubility of 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium Chloride

The solubility characteristics of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride are of notable interest due to the presence of both organic and ionic components in its structure. Understanding its solubility is key in various applications, especially in pharmacology and organic synthesis.

Factors Influencing Solubility

Several factors influence the solubility of this compound:

  • Polarity: The dimethoxy groups contribute to the polar nature of the molecule, which may enhance its solubility in polar solvents.
  • Ionization: The quaternary ammonium ion (from the tetrahydroisoquinolin-2-ium part) can influence solubility in water, potentially increasing it due to ionic interactions.
  • Temperature: Like many compounds, solubility can vary with temperature; increased temperatures often lead to increased solubility.

Expected Behavior in Solvents

It is likely that:

  1. This compound is soluble in water due to its ionic nature as a chloride salt.
  2. It may exhibit higher solubility in polar organic solvents compared to non-polar solvents, making it versatile in various chemical environments.

In summary, while precise solubility values may vary, the combination of polar functional groups and ionic characteristics suggest that 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride is likely to be soluble in polar solvents, particularly water. Further experimental data would provide a clearer perspective on its solubility profile in specific conditions.

Interesting facts

6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride

This fascinating compound, known as 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride, belongs to a class of compounds called isoquinolines. These are particularly interesting in the field of medicinal chemistry due to their diverse biological activities.

Interesting Insights

  • Biological Activity: Isoquinoline derivatives, such as this compound, have been found to exhibit a wide range of pharmacological effects including antioxidant, analgesic, and anti-inflammatory properties.
  • Structural Chemistry: The tetrahydroisoquinoline structure contributes to the compound's unique chemical reactivity, allowing it to participate in various chemical transformations.
  • Research Relevance: Compounds that resemble this structure are currently under investigation for their potential roles in treating neurological disorders, offering promising avenues for drug discovery.
  • Complex Synthesis: The synthesis of this compound involves intricate organic reactions, showcasing the creativity and expertise required in modern organic chemistry.

As you explore the world of isoquinoline derivatives, it's crucial to understand their profound impact on pharmaceutical development. As scientists continue to study compounds like 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride, we may unlock new therapeutic mechanisms that could revolutionize treatments for various diseases.

In conclusion, this compound not only serves as a structural novelty but also encapsulates the excitement of ongoing research in drug discovery and the intricate relationships between chemical structure and biological activity.

Synonyms
Heliamine hydrochloride
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinoline hydrochloride
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-, HYDROCHLORIDE
NSC 18443
Isoquinoline, 6,7-dimethoxy-1,2,3,4-tetrahydro-, hydrochloride