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Tropisetron hydrochloride

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Identification
Molecular formula
C17H21ClN2O2
CAS number
105826-92-4
IUPAC name
6,7-dimethoxy-2-pentyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
State
State

The compound is generally in a solid state at room temperature, typically appearing as a powder or crystalline solid. It is stable under normal conditions and is hygroscopic, meaning it can absorb moisture from the air.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
325.00
Boiling point (Kelvin)
598.15
General information
Molecular weight
416.95g/mol
Molar mass
416.9540g/mol
Density
1.1860g/cm3
Appearence

Tropisetron hydrochloride is a white or almost white crystalline powder. It is typically odorless or may have a mild odour. The solid form can vary slightly based on processing and storage conditions.

Comment on solubility

Solubility of 6,7-Dimethoxy-2-pentyl-1,2,3,4-tetrahydroisoquinolin-2-ium Chloride

The solubility of 6,7-dimethoxy-2-pentyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride is influenced by several factors due to its complex structure. Here are some key points to consider:

  • Polarity: The presence of methoxy groups generally increases polarity, facilitating solubility in polar solvents such as water.

  • Ionization: As a quaternary ammonium salt (being a chloride), it is likely to be soluble in water due to the action of ionization, where it dissociates into its constituent ions.

  • Hydrophobic vs. Hydrophilic: The pentyl chain introduces a hydrophobic character which can hinder solubility in highly polar environments. However, the overall solubility will depend on the balance between this hydrophobic part and the polar functional groups.

  • Solvent Choices: Generally, it is expected to be more soluble in organic solvents like methanol or ethanol compared to water, owing to its complex organic structure.

In conclusion, while 6,7-dimethoxy-2-pentyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride likely exhibits a degree of solubility in various solvents, exact solubility characteristics can vary based on specific conditions such as temperature and solvent polarity. Thus, experimental determination may be necessary to elucidate its solubility profile fully.

Interesting facts

Interesting Facts about 6,7-dimethoxy-2-pentyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride

The compound 6,7-dimethoxy-2-pentyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride is a fascinating chemical with a unique structure and potential applications. Understanding its components reveals much about its significance in the field of chemistry:

  • Complex Structure: This compound features a tetrahydroisoquinolin ionic structure, which is noteworthy for its specific arrangement of carbon, nitrogen, and oxygen atoms. The isoquinoline ring is known for its biological activity.
  • Potential Biological Activities: Compounds containing isoquinoline moieties are often studied for their pharmacological properties. They may exhibit effects such as antioxidant, anti-inflammatory, and antitumor activities, making this compound particularly interesting for medicinal chemistry.
  • Dimethoxy Groups: The presence of methoxy groups at the 6 and 7 positions of the isoquinoline ring can enhance lipophilicity, potentially improving the compound’s bioavailability and interaction with biological targets.
  • Chloride Counterion: The chloride ion as a counterion can influence the solubility and stability of the compound. Moreover, chloride ions in ionic compounds play an important role in various biological systems.
  • Pentyl Side Chain: The pentyl group introduces hydrophobic properties. This may help in the compound's ability to traverse biological membranes, which is essential for drug design.

This compound is a prime example of how intricate organic structures can lead to meaningful biological interactions and therapeutic potential. As research continues in fields such as pharmacology and biotechnology, compounds like 6,7-dimethoxy-2-pentyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride will certainly capture the attention of scientists seeking to unlock new biochemical pathways.

Synonyms
1,2,3,4-Tetrahydro-2-amyl-6,7-dimethoxyisoquinoline hydrochloride
6275-10-1
NSC 33545
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-pentylisoquinoline hydrochloride
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2-PENTYL-, HYDROCHLORIDE