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Tetrahydropapaverine hydrochloride

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Identification
Molecular formula
C12H20ClNO2
CAS number
3490-15-1
IUPAC name
6,7-dimethoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium;chloride
State
State

At room temperature, it is solid.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
287.80g/mol
Molar mass
287.7970g/mol
Density
1.2200g/cm3
Appearence

Tetrahydropapaverine hydrochloride appears as a white to off-white crystalline powder, which may become slightly yellowish upon exposure to air over time.

Comment on solubility

Solubility of 6,7-Dimethoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; Chloride

The solubility of 6,7-dimethoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride in various solvents is influenced by its ionic nature and structural properties. Generally, the following points can be outlined regarding its solubility:

  • Water Solubility: Ionic compounds typically exhibit good solubility in polar solvents like water. As a quaternary ammonium compound, this specific compound is expected to be highly soluble in water.
  • Organic Solvents: Conversely, the compound's behavior in non-polar or less polar organic solvents (e.g., hexane, toluene) might show limited solubility due to the hydrophilic nature of its ionic portion.
  • Effect of pH: The solubility can also change with the pH of the solvent, as the protonation state of certain functional groups plays a critical role in solubility dynamics.

In a practical sense, a common statement often referenced in the study of solubility is: "Like dissolves like." This means that compounds will generally dissolve well in solvents that have similar polarity. Thus, understanding the environment in which the compound is placed will greatly assist in predicting its solubility behavior.

In summary, the solubility profile of 6,7-dimethoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium; chloride emphasizes its affinity for polar solvents, primarily water, while showcasing limited interactions with non-polar environments.

Interesting facts

Interesting Facts About 6,7-Dimethoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium Chloride

This fascinating compound, known as 6,7-dimethoxy-2,3-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride, belongs to a class of compounds called isoquinolines, which are structurally related to the well-known alkaloids. Here are some noteworthy aspects of this intriguing chemical:

  • Alkaloid Family: Isoquinolines are often associated with the behavior of various biological systems and can possess interesting pharmacological properties.
  • Potential Applications: Compounds like this one have been explored for their potential in developing medicinal therapies. Some derivatives show promise in treating conditions such as neurological disorders.
  • Synthesis: The synthesis of this compound showcases the amazing capability of organic chemistry to craft complex architectures through various reaction mechanisms. Chemists utilize methods like reduction and alkylation to achieve the desired structure.
  • Biological Interest: Research into alkaloids indicates they may exhibit various biological activities, including antimicrobial, anti-inflammatory, and antioxidant effects.
  • Research Frontier: Ongoing studies are delving into the potential effects of this compound on neurotransmitter systems, which may lead to new insights in pharmacology.

As a chemistry student or researcher, exploring compounds like this not only enhances your understanding of chemical behavior but also underscores the importance of organic compounds in biomedical research. There is much to discover in the realm of small molecules and their impact on health and medicine!

Synonyms
1,2,3,4-Tetrahydro-6,7-dimethoxy-2,3-dimethylisoquinoline hydrochloride
6274-98-2
NSC 33528
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6,7-DIMETHOXY-2,3-DIMETHYL-, HYDROCHLORIDE