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6,7-Dimethoxy-2,3-dimethyl-3,4-dihydroisoquinoline

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Identification
Molecular formula
C13H19NO2
CAS number
1772-99-4
IUPAC name
6,7-dimethoxy-2,3-dimethyl-3,4-dihydro-1H-isoquinoline
State
State
At room temperature, this compound is a solid.
Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
205.27g/mol
Molar mass
205.2720g/mol
Density
1.0481g/cm3
Appearence
6,7-Dimethoxy-2,3-dimethyl-3,4-dihydroisoquinoline typically appears as a colorless crystalline solid.
Comment on solubility

Solubility of 6,7-dimethoxy-2,3-dimethyl-3,4-dihydro-1H-isoquinoline

The solubility of 6,7-dimethoxy-2,3-dimethyl-3,4-dihydro-1H-isoquinoline can be influenced by several factors, including the chemical structure and the presence of functional groups. This compound, belonging to the isoquinoline class, exhibits properties that can lead to diverse solubility characteristics:

  • Polarity: The presence of methoxy groups (-OCH3) suggests potential for solubility in polar solvents such as water or ethanol, but overall solubility may be limited due to the hydrophobic nature of the isoquinoline ring.
  • Solvent Interaction: The compound may show improved solubility in organic solvents like dichloromethane or dimethyl sulfoxide (DMSO), where nonpolar characteristics can be mitigated by favorable interactions.
  • Temperature Dependency: As with many organic compounds, solubility can increase with temperature, allowing for greater dissolution in various solvents at elevated temperatures.

In conclusion, the solubility of 6,7-dimethoxy-2,3-dimethyl-3,4-dihydro-1H-isoquinoline is not straightforward and remains a complex interplay of its structural features and the solvent environment. Understanding this solubility behavior is crucial for applications in pharmaceutical and chemical synthesis. This highlights the importance of solvent choice and temperature in solubility studies.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-2,3-dimethyl-3,4-dihydro-1H-isoquinoline

This fascinating compound belongs to the class of isoquinolines, renowned for their structural diversity and biological activity. Here are some noteworthy aspects:

  • Unique structure: The presence of multiple methoxy and methyl groups gives this isoquinoline its unique properties, influencing both its chemical reactivity and biological activities.
  • Biological relevance: Isoquinolines are well-known for their roles in medicinal chemistry. Compounds in this class exhibit a range of activities including antitumor, antidepressant, and even antioxidant properties.
  • Synthetic pathways: The synthesis of such complex molecules can involve various innovative approaches, including Pauson-Khand reactions and applications of transition metal catalysis.
  • Research Potential: Ongoing research investigates how varying substituents, like the two methoxy and two methyl groups, can affect the compound's interaction with biological systems. This makes it a promising candidate for drug discovery and development.
  • Natural occurrence: Compounds similar to this isoquinoline are often sourced from plants, particularly those in the Ranunculaceae family, highlighting the fascinating intersection of chemistry and nature.

As scientists delve deeper into such compounds, they uncover their potential not just for therapeutic applications but also their significance in understanding fundamental biochemical pathways. The intricate connectivity within isoquinolines continues to inspire innovative research in organic chemistry and pharmacology.

Synonyms
1,2,3,4-Tetrahydro-6,7-dimethoxy-2,3-dimethylisoquinoline
5884-23-1
SCHEMBL8034387
DTXSID701195106