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Noscapine

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Identification
Molecular formula
C22H23NO7
CAS number
128-62-1
IUPAC name
6,7-dimethoxy-3-(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)-3H-isobenzofuran-1-one
State
State

At room temperature, noscapine is in a solid state. It is typically available as a crystalline powder.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
459.80
Boiling point (Kelvin)
732.95
General information
Molecular weight
413.43g/mol
Molar mass
413.4520g/mol
Density
1.1774g/cm3
Appearence

Noscapine typically appears as a white, crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 6,7-dimethoxy-3-(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)-3H-isobenzofuran-1-one

The solubility of the compound with the formula C22H23NO7, specifically known as 6,7-dimethoxy-3-(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)-3H-isobenzofuran-1-one, can be evaluated by considering several factors that influence solubility:

  • Polarity: This compound exhibits a moderate level of polarity due to the presence of methoxy groups and a nitrogen atom, which can influence its interaction with solvents.
  • Solvent Compatibility: It tends to show better solubility in organic solvents such as ethanol and DMSO compared to water, highlighting its lipophilic character.
  • Hydrophobic Interactions: The isobenzofuran structure may contribute to hydrophobic interactions, limiting solubility in polar solvents.
  • Structural Complexity: The intricate structure introduces specific steric factors that may further affect the solubility profile.

In summary, while insights into the exact solubility parameters can vary, this compound is likely to be more soluble in organic solvents than in aqueous solutions due to its structural features and polarity characteristics. Understanding these dynamics is crucial for applications in various fields, including pharmacology and material sciences.

Interesting facts

Interesting Facts About 6,7-Dimethoxy-3-(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)-3H-isobenzofuran-1-one

The compound 6,7-dimethoxy-3-(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)-3H-isobenzofuran-1-one is a fascinating molecule with unique structural features that contribute to its potential biological activities. This compound can be categorized as a derivative of isobenzofuran, which is known for its diverse applications in medicinal chemistry.

Structural Highlights

  • Dimethoxy Substitution: The presence of the two methoxy groups sits at the 6 and 7 positions, which can significantly influence the compound's interactions with biological targets.
  • Isoquinoline Unit: Incorporating a 3,4-dihydro-1H-isoquinoline moiety at the 3-position adds complexity and has been linked to various pharmacological properties.

Potential Applications

Due to its intricate structure, this compound has been researched for various applications, which include:

  • Pharmaceutical Development: Potential candidates for therapeutic agents, particularly in neurology and psychiatry.
  • Biological Activity: Studies suggest it may exhibit antioxidant, neuroprotective, and anti-inflammatory properties.
  • Targeted Research: Derivatives are often explored in drug discovery programs, aiming to enhance efficacy and reduce side effects.

Research Significance

Understanding its mechanisms of action could provide insights into:

  • Drug Design: Insights gained from studying structures like this can lead to more effective drug candidates.
  • Matrix of Composition: The combination of heterocycles often leads to increased polarity and solubility, which are crucial for biological activity.

As research continues, this compound illustrates the importance of chemical innovation in the quest for new and effective treatments. The exploration of compounds like 6,7-dimethoxy-3-(2-methyl-3,4-dihydro-1H-isoquinolin-1-yl)-3H-isobenzofuran-1-one not only enriches our understanding of organic chemistry but also enhances our ability to combat medical challenges.