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Noscapine

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Identification
Molecular formula
C22H23NO7
CAS number
128-62-1
IUPAC name
6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one
State
State

Noscapine is a solid at room temperature and is typically found in its crystalline powder form.

Melting point (Celsius)
176.00
Melting point (Kelvin)
449.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
413.44g/mol
Molar mass
413.4380g/mol
Density
1.2000g/cm3
Appearence

Noscapine appears as a crystalline powder that is white or almost white. It is known for having a slightly bitter taste.

Comment on solubility

Solubility of 6,7-Dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one

The solubility of complex organic compounds, such as 6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one, can vary significantly depending on several factors. Understanding these factors can help in predicting the behavior of the compound in different environments.

Factors Affecting Solubility

  • Polarity: The presence of multiple methoxy groups suggests moderate polarity, which may enhance solubility in polar solvents like water and alcohols.
  • Molecular Structure: The intricate structure of the compound, including its isoquinoline and isobenzofuran components, can lead to a complex interaction with solvents.
  • Temperature: Increasing the temperature often enhances solubility; thus, testing at various temperatures may yield different results.
  • pH Levels: The solubility may also change depending on the acidic or basic nature of the solution, which can affect ionization and solvation.

In summary, while detailed solubility data for this specific compound may not be extensively documented, its various functional groups indicate a potential for solubility in polar solvents, with additional considerations needed for environmental conditions. Understanding the solubility can be crucial for applications in pharmaceuticals and agrochemicals.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one

This compound presents a fascinating example of complex organic chemistry, showcasing the intricate design and synthesis of molecular structures. Here are some intriguing aspects to consider:

  • Structural Complexity: The molecular architecture includes various functional groups and rings, specifically the isoquinoline structure, which is often found in many biologically active compounds.
  • Potential Biological Activity: Compounds like this one often display a range of biological properties. Research indicates that isoquinoline derivatives can exhibit anti-cancer, anti-inflammatory, and antimicrobial activities, making them subjects of interest for pharmaceutical research.
  • Natural vs. Synthetic: While some isoquinolines are derived from natural sources, this compound is typically synthesized in the lab, showcasing the advances in synthetic organic chemistry.
  • Functionalization: The presence of multiple methoxy groups indicates a degree of functionalization that can greatly influence the compound's reactivity and potential uses.
  • Relationship to Natural Products: Compounds like this may be inspired by natural products such as alkaloids, which have potent biochemical effects and are often modified to enhance efficacy or reduce toxicity.

As a student or researcher, understanding such compounds can open pathways to discovering novel therapeutic agents. According to a famous quote by chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Exploring such chemically rich structures can lead to significant breakthroughs in medicinal chemistry and drug development.

In conclusion, 6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one is more than just a compound; it is a key to understanding the complexity and beauty of organic synthesis and its applications in health and disease.

Synonyms
6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-2-benzofuran-1-one
6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one
DivK1c_000323
SCHEMBL14386820
CHEBI:95149
KBio1_000323
NINDS_000323
AKOS003673314
IDI1_000323
AS-56145
Q27166942