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Galanthamine hydrobromide

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Identification
Molecular formula
C17H20NO4
CAS number
64068-64-0
IUPAC name
6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-isobenzofuran-1-one;chloride
State
State

At room temperature, this compound is a solid. It may be offered as a crystalline solid or potentially as a fine powder.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
346.80
Boiling point (Kelvin)
619.95
General information
Molecular weight
368.88g/mol
Molar mass
368.8620g/mol
Density
1.4700g/cm3
Appearence

The compound typically appears as a white or off-white crystalline powder, often depending on its level of hydration. As many isoquinoline derivatives, it can exhibit slight variances in color or texture based on crystal purity.

Comment on solubility

Solubility of 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-isobenzofuran-1-one;chloride

The solubility of the compound 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-isobenzofuran-1-one; chloride can be influenced by several factors given its complex structure:

  • Polarity: The presence of various functional groups, particularly methoxy (-OCH3) and the ammonium cation, contributes to the overall polarity of the compound, which can enhance solubility in polar solvents such as water.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the presence of hydroxyl groups can also play a significant role in solubility, allowing the compound to interact favorably with solvent molecules.
  • Solvent Properties: Solubility can vary significantly depending on the solvent used. Typically, organic solvents like ethanol and methanol may provide a better solubility profile compared to non-polar solvents.
  • Concentration and Temperature: As with many compounds, increasing the temperature often leads to increased solubility. Concentration also plays a role; saturation limits must be considered during experimentation.

In summary, while some structural features suggest enhanced solubility in aqueous solutions, it is essential to conduct specific solubility tests to determine the most effective solvent and conditions for the use of 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-isobenzofuran-1-one; chloride. As with most compounds, empirical data will provide the most reliable information regarding its solubility behavior.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-3-[(5S)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-3H-isobenzofuran-1-one; Chloride

This compound, a complex organic molecule, stands out in the field of medicinal chemistry due to its intricate structure and potential bioactivity. It exhibits multiple features that make it a subject of intrigue:

  • Biodiversity in Structure: The molecule features a rich array of functional groups which is typical for alkaloids. The presence of both a dioxole and isoquinoline structure suggests interesting interactions with biological systems.
  • Potential Pharmacological Activities: Compounds like this one are often researched for neuroprotective and anti-tumor properties. The isoquinoline skeleton is a common motif in drugs targeting neurological disorders.
  • Synthesis Challenges: The synthetic pathway to formulate this compound may be elaborate, often involving multi-step reactions that require precise conditions and careful handling of reagents to achieve high yield and purity.
  • Experimental Use: In experimental studies, the compound may serve as a valuable tool for understanding specific pathways in cellular mechanisms, particularly those related to neurotransmission and cancer biology.
  • Natural Inspiration: The inspiration for such synthetic compounds often arises from natural products, showcasing the synergy between nature and synthetic organic chemistry.

As chemists continue to explore the unique properties of this compound, it may reveal insights into new therapeutic avenues. Its complex design not only represents a challenge in synthesis but also embodies the continuous quest to unlock the potential of organic molecules in addressing human health.

In essence, the study of this compound epitomizes the advancements in chemical research and the ongoing commitment to discovering novel solutions through the lens of organic chemistry.

Synonyms
SCHEMBL1405962
AKOS026749990
(5S)-5-(4,5-dimethoxy-3-oxo-1H-2-benzofuran-1-yl)-4-methoxy-6-methyl-2H,5H,6H,7H,8H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium chloride