Skip to main content

Tetrahydropalmatine

ADVERTISEMENT
Identification
Molecular formula
C21H25NO5
CAS number
2934-97-6
IUPAC name
6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one
State
State

Solid at room temperature.

Melting point (Celsius)
149.50
Melting point (Kelvin)
422.65
Boiling point (Celsius)
428.70
Boiling point (Kelvin)
701.85
General information
Molecular weight
355.44g/mol
Molar mass
355.3720g/mol
Density
1.3000g/cm3
Appearence

Tetrahydropalmatine typically appears as a white or off-white crystalline powder.

Comment on solubility

Solubility of 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one

The solubility of the compound 6,7-dimethoxy-3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one can be influenced by various factors. Due to its complex structure, which includes multiple methoxy groups and fused ring systems, predicting solubility in different solvents requires careful consideration. Key points to note include:

  • Polarity: The presence of methoxy groups contributes to polar characteristics, suggesting better solubility in polar solvents.
  • Hydrophobic Regions: The isoquinoline structure may introduce some hydrophobic properties, making it less soluble in highly polar solvents.
  • pH Sensitivity: The compound may exhibit different solubility profiles at varying pH levels, as protonation states can affect solubility.
  • Temperature Effects: Like many organic compounds, higher temperatures may enhance solubility.
  • Solvent Compatibility: It may be more soluble in organic solvents such as methanol, ethanol, or dimethyl sulfoxide (DMSO) rather than in water.

In conclusion, the solubility of this compound is expected to be moderate in polar solvents, while achieving limited solubility in apolar solvents. Understanding these properties is essential for its future applications in pharmaceuticals and material science.

Interesting facts

Exploring 6,7-Dimethoxy-3-[(5S)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-3H-isobenzofuran-1-one

This fascinating compound belongs to a class of molecules known for their complexity and potential biological activities. Here are some interesting insights:

  • Unique Structure: The compound features a remarkable structure that integrates multiple functional groups, showcasing the beauty of chemical diversity in organic synthesis.
  • Potential Pharmacological Applications: Compounds like this are often studied for their possible therapeutic effects. Research into similar structures has revealed activities such as antioxidant, antimicrobial, and even anti-cancer properties.
  • Dioxoloisoquinoline Derivatives: The presence of the dioxoloisoquinoline framework suggests the compound may interact with biological systems in unique ways, potentially influencing pathways relevant to human health.
  • Synthetic Interest: The complexity of its synthesis can provide significant challenges and intrigue for chemists looking to innovate new synthetic methods or explore reaction conditions effectively.
  • Chirality: The chirality in part of its structure may lead to different biological activities depending on the stereoisomer, making the study of this compound not only scientifically stimulating but also crucial for drug development.

As we delve deeper into the study of such compounds, we unlock new doors to understanding biological mechanisms and developing innovative therapeutic agents. These discoveries illustrate the intricate connections between chemistry and life, driving forward the fields of medicinal chemistry and pharmacology.

Synonyms
CHEMBL1623561