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6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline

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Identification
Molecular formula
C12H17NO2
CAS number
69605-93-0
IUPAC name
6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline
State
State

At room temperature, 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline is typically in a solid state. It maintains its integrity in this form under normal environmental conditions.

Melting point (Celsius)
84.00
Melting point (Kelvin)
357.15
Boiling point (Celsius)
253.50
Boiling point (Kelvin)
526.65
General information
Molecular weight
207.28g/mol
Molar mass
207.2760g/mol
Density
1.1345g/cm3
Appearence

6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline typically appears as a solid substance. The compound may be presented as a crystalline powder or crystalline solid, known for its white to off-white color, depending on its purity and particle size.

Comment on solubility

Solubility of 6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline

The solubility of 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline can be influenced by various factors, including its chemical structure and the nature of the solvent. Here are some key points to consider when evaluating its solubility:

  • Polarity: The presence of methoxy groups in the structure generally increases the polarity of the compound, which can enhance its solubility in polar solvents like water.
  • Hydrophobic Character: The tetrahydroisoquinoline moiety may contribute hydrophobic characteristics, leading to decreased solubility in highly polar solvents.
  • Common Solvents: This compound may be more soluble in organic solvents, such as ethanol or methanol, due to the hydrophobic regions of its structure.
  • Temperature Dependency: Like most organic compounds, solubility is likely to increase with temperature, allowing for greater dissolution in the solvent.
  • pH Influence: Changes in pH can also affect solubility, particularly if the compound can exist in different protonation states.

Understanding these nuances is essential for practical applications, such as drug formulation and synthesis, where solubility plays a critical role. As the saying goes, "solubility is the pathway to reactivity," emphasizing how crucial it is for chemists to grasp the solubility dynamics of compounds like 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline

6,7-Dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline is a fascinating compound that belongs to a class of organic compounds known as isoquinolines. These compounds have drawn significant interest due to their diverse biological activities and potential therapeutic applications.

Biological Significance

This compound is particularly notable for its:

  • Neuroprotective properties: Studies have suggested that isoquinoline derivatives may have a protective effect on neurons and could play a role in the treatment of neurodegenerative diseases.
  • Antioxidant activity: Compounds like 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline are known for their ability to combat oxidative stress, which is crucial in preventing cellular damage.
  • Pharmacological potential: The unique structure of this compound allows it to interact with multiple biological targets, making it a candidate for further investigation as a pharmaceutical agent.

Chemical Structure

The structure of 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline incorporates:

  • A tetrahydroisoquinoline core, which provides a rigid framework conducive to biological activity.
  • Two methoxy groups, which are known to enhance lipophilicity and potentially improve bioavailability.
  • A methyl group that may play a role in the compound's interaction with biological targets.

Research and Development

The compound is of great interest within the research community because:

  • It serves as a precursor for synthesis of other complex molecules.
  • It is being explored for its potential use in developing new drugs to target various disease states.
  • It represents a vital area of study for chemists and pharmacologists aiming to innovate therapeutic solutions.

As research continues, the journey of 6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline will undoubtedly reveal more about its potential and significance in both organic chemistry and pharmaceutical sciences.

Synonyms
6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydroisoquinoline
249624-84-8
SCHEMBL1011095
SRXUBSWMMKWIBE-UHFFFAOYSA-N
AKOS022196454
DA-07710
6,7-dimethoxy-3-methyl-1,2,3,4-tetrahydro-isoquinoline