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6,7-Dimethoxy-3,4-dihydroisoquinoline

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Identification
Molecular formula
C11H13NO2
CAS number
30548-81-1
IUPAC name
6,7-dimethoxy-3,4-dihydroisoquinoline
State
State
At room temperature, 6,7-Dimethoxy-3,4-dihydroisoquinoline is typically in a solid state, forming crystalline structures.
Melting point (Celsius)
77.00
Melting point (Kelvin)
350.00
Boiling point (Celsius)
328.50
Boiling point (Kelvin)
601.70
General information
Molecular weight
193.23g/mol
Molar mass
193.2320g/mol
Density
1.2202g/cm3
Appearence

6,7-Dimethoxy-3,4-dihydroisoquinoline typically appears as a crystalline solid. The specific color and form can vary depending on purity and the exact form of crystallization, but it is usually a colorless to off-white solid.

Comment on solubility

Solubility of 6,7-Dimethoxy-3,4-Dihydroisoquinoline

The solubility of 6,7-dimethoxy-3,4-dihydroisoquinoline can be quite complex, depending on several factors. Generally, compounds with multiple methoxy groups exhibit varying degrees of solubility in organic solvents. Here are some key points to consider:

  • Polar vs Non-Polar Solvents: This compound is likely to show better solubility in non-polar solvents due to the hydrophobic nature of the isoquinoline structure.
  • Temperature Effects: Increasing temperature often enhances solubility; thus, heating may facilitate its dissolution in certain solvents.
  • pH Sensitivity: The solubility can also vary with pH levels, which may affect the ionization of functional groups in the compound.
  • Concentration: At higher concentrations, solubility can decrease due to potential aggregation or precipitation of the compound.

In conclusion, 6,7-dimethoxy-3,4-dihydroisoquinoline's solubility is influenced by its molecular structure and environmental conditions. To accurately determine its solubility, experimental validations in various solvents are essential.

Interesting facts

Interesting Facts about 6,7-Dimethoxy-3,4-dihydroisoquinoline

6,7-Dimethoxy-3,4-dihydroisoquinoline is a fascinating compound that belongs to the isoquinoline family, which is known for its diverse range of biological activities. Here are some intriguing points:

  • Structural Dynamics: The compound features a bicyclic structure, which contributes to its unique properties and potential interactions with biological systems. The presence of methoxy groups at the 6 and 7 positions adds to its chemical versatility.
  • Biological Relevance: Isoquinolines are often studied for their medicinal properties. Compounds within this class, including 6,7-dimethoxy-3,4-dihydroisoquinoline, have been investigated for their roles in various pharmacological activities, including anti-inflammatory and neuroprotective effects.
  • Natural Occurrence: Some isoquinoline derivatives are naturally occurring and found in various plant species, which are utilized in traditional medicine for their therapeutic effects. This raises interest in the potential of synthesized analogs.
  • Chemical Modifications: The methoxy substitutions in this compound open up avenues for further chemical modifications, allowing scientists to create derivatives with enhanced biological profiles or targeted functionalities.
  • Synthesis Exploration: The synthesis of 6,7-dimethoxy-3,4-dihydroisoquinoline is a subject of interest in synthetic organic chemistry, offering students and researchers practical insights into reaction mechanisms and the importance of stereochemistry in compound formation.

In summary, 6,7-dimethoxy-3,4-dihydroisoquinoline holds significant potential for exploration in medicinal chemistry, providing a rich area for research and development aimed at discovering new therapeutic agents.

Synonyms
3382-18-1
3,4-Dihydro-6,7-dimethoxyisoquinoline
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-
DEHYDROHELIAMINE
D6LM439T76
EINECS 222-185-9
NSC-627588
3,4-DIHYDROBACKEBERGINE
DTXSID90187475
DTXCID00109966
222-185-9
RefChem:486183
6,7-Dimethoxy-3,4-dihydroisoquinoline
6,7-Dimethoxy-3,4-dihydro-isoquinoline
MFCD00266748
NSC627588
6,7-Bis-(d3)-methoxy-3,4-dihydroisoquinoline (N-1)
Oprea1_728067
SCHEMBL251439
UNII-D6LM439T76
SCHEMBL1705780
CHEMBL1998359
SCHEMBL31268130
BCP26090
STK801978
AKOS005622725
AC-9612
DS-2063
3,4-dihydro-6,7-dimethoxy-isoquinoline
NCI60_008813
SY029548
DB-029200
CS-0150551
D5046
NS00049234
EN300-104837
382D181
6 pound not7-Dimethoxy-3 pound not4-dihydroisoquinoline
InChI=1/C11H13NO2/c1-13-10-5-8-3-4-12-7-9(8)6-11(10)14-2/h5-7H,3-4H2,1-2H