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Quinazoline compound

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Identification
Molecular formula
C13H16N4O2
CAS number
NA
IUPAC name
6,7-dimethoxy-N2,N2-dimethyl-quinazoline-2,4-diamine
State
State

At room temperature, this compound is generally found in a solid state.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
269.50
Boiling point (Kelvin)
542.60
General information
Molecular weight
260.30g/mol
Molar mass
260.3030g/mol
Density
1.2300g/cm3
Appearence

The compound typically appears as a crystalline solid. It may appear white or off-white in color.

Comment on solubility

Solubility of 6,7-dimethoxy-N2,N2-dimethyl-quinazoline-2,4-diamine

The solubility of 6,7-dimethoxy-N2,N2-dimethyl-quinazoline-2,4-diamine in various solvents can be intriguing due to its unique structural features.

  • Polar Solvents: This compound may exhibit limited solubility in polar solvents such as water, owing to the presence of multiple methoxy groups which can affect hydrogen bonding.
  • Non-Polar Solvents: Conversely, it is likely to show better solubility in non-polar organic solvents (e.g., chloroform or ethyl acetate) due to its hydrophobic characteristics.
  • pH Dependence: The solubility might also be influenced by the pH of the solution. In acidic conditions, the availability of protons could enhance solubility through protonation, which may increase its overall interaction with the solvent.

Furthermore, the effectiveness of solubility can also be attributed to:

  • The molecular size of the compound, which can impact its ability to dissolve.
  • The presence of functional groups that may facilitate or hinder solubility due to steric hindrance or favorable interactions.

As always, it is crucial to conduct empirical tests to ascertain the precise solubility profile, as theoretical predictions may vary.

Interesting facts

Interesting Facts about 6,7-dimethoxy-N2,N2-dimethyl-quinazoline-2,4-diamine

6,7-dimethoxy-N2,N2-dimethyl-quinazoline-2,4-diamine is a fascinating compound that belongs to the class of quinazoline derivatives. These compounds have garnered much attention in the field of medicinal chemistry due to their diverse biological activities. Here are some intriguing facts about this compound:

  • Potential Pharmaceutical Applications: Quinazoline derivatives, including this compound, have been studied for their potential in developing new therapeutics against various diseases. They often exhibit anticancer, anti-inflammatory, and antimicrobial properties.
  • Mechanism of Action: Many quinazoline derivatives exert their effects through the inhibition of specific kinases, making them valuable in targeting cancer and other diseases characterized by abnormal cell signaling.
  • Synthetic Versatility: The synthesis of quinazoline derivatives can be accomplished through various methods, allowing for structural modifications that can enhance their biological activity and optimize their effectiveness in treating diseases.
  • Research Significance: This compound, due to its unique structure, is of significant interest in drug discovery. Researchers are exploring derivatives and analogs of this compound to identify more effective therapeutic agents.

As emphasized in numerous studies, the importance of structure-activity relationship (SAR) analysis in this field cannot be overstated. It helps chemists to understand how modifications to the compound can influence its pharmacological profile. Exciting discoveries and advancements in this area hint at a promising future for quinazoline derivatives, including 6,7-dimethoxy-N2,N2-dimethyl-quinazoline-2,4-diamine.

In conclusion, as a chemistry enthusiast, one should keep an eye on the developments surrounding this intriguing compound. With ongoing research, who knows what new horizons may be discovered?

Synonyms
19216-53-6
N2VRC6C8HU
UNII-N2VRC6C8HU
6,7-Dimethoxy-N2,N2-dimethyl-2,4-quinazolinediamine
NSC 403405
NSC-403405
2,4-Quinazolinediamine, 6,7-dimethoxy-N2,N2-dimethyl-
Alfuzosin hydrochloride impurity F [EP]
ALFUZOSIN HYDROCHLORIDE IMPURITY F [EP IMPURITY]
ALFUZOSIN HYDROCHLORIDE IMPURITY F (EP IMPURITY)
Alfuzosin hydrochloride impurity F
RefChem:197392
6,7-Dimethoxy-N2,N2-dimethylquinazoline-2,4-diamine
6,7-dimethoxy-2-N,2-N-dimethylquinazoline-2,4-diamine
MLS000047893
SMR000033893
6,7-dimethoxy-N~2~,N~2~-dimethylquinazoline-2,4-diamine
ChemDiv2_004346
CHEMBL8683
Oprea1_796537
SCHEMBL11046169
BDBM96939
cid_6602978
HMS1381F12
DNDI1416995
UAA21653
CCG-23928
AKOS001680309
IDI1_003061
EU-0049418
EN300-1720194
AH-262/31834011
Z2718845622
6,7-dimethoxy-N~2~,N~2~-dimethyl-2,4-quinazolinediamine
6,7-dimethoxy-N2,N2-dimethyl-quinazoline-2,4-diamine;hydrochloride
6,7-dimethoxy-N2,N2-dimethylquinazoline-2,4-diamine;hydrochloride
(4-amino-6,7-dimethoxy-quinazolin-2-yl)-dimethyl-amine;hydrochloride
2,4-Quinazolinediamine, 6,7-dimethoxy-N2,N2-dimethyl-; Quinazoline, 4-amino-2-(dimethylamino)-6,7-dimethoxy- (8CI); 6,7-Dimethoxy-N2,N2-dimethyl-2,4-quinazolinediamine; NSC 403405; Alfuzosin Hydrochloride Imp. F (EP)