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6,7-Dimethoxyquinolin-4-amine

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Identification
Molecular formula
C11H12N2O2
CAS number
25559-12-2
IUPAC name
6,7-dimethoxyquinolin-4-amine
State
State

At room temperature, 6,7-Dimethoxyquinolin-4-amine is in a solid state.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.20
Boiling point (Celsius)
372.50
Boiling point (Kelvin)
645.60
General information
Molecular weight
218.23g/mol
Molar mass
218.2480g/mol
Density
1.2496g/cm3
Appearence

6,7-Dimethoxyquinolin-4-amine typically appears as a solid substance. The color can vary but generally presents as an off-white to light yellow powder. Its physical state and purity can affect the precise appearance. No significant odor is usually associated with this compound.

Comment on solubility

Solubility of 6,7-Dimethoxyquinolin-4-amine

The solubility of 6,7-dimethoxyquinolin-4-amine can be an intriguing aspect of its chemical properties, influencing its applications in various fields. Here are some key points to consider:

  • Polarity: The presence of methoxy groups can affect the overall polarity of the compound, which may enhance its solubility in organic solvents.
  • Solvent Compatibility: It is likely to be soluble in solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), while its solubility in water may be limited due to the bulky aromatic structure.
  • Hydrogen Bonding: The amine group can participate in hydrogen bonding, potentially increasing solubility in certain polar environments.
  • pH Influence: The solubility may vary with changes in pH, as the protonation of the amine can enhance solubility in acidic conditions.

Overall, understanding the solubility of 6,7-dimethoxyquinolin-4-amine is crucial for optimizing its use in formulations, biological assays, or synthesis processes. For practical applications, it is advised to conduct empirical solubility tests in the intended solvents to obtain accurate data.

Interesting facts

Interesting Facts about 6,7-Dimethoxyquinolin-4-amine

6,7-Dimethoxyquinolin-4-amine is a fascinating compound that belongs to the quinoline family, known for its diverse range of biological activities. This compound presents an intriguing structure that opens avenues for various applications in medicinal chemistry.

Biological Significance

This compound has been studied for its potential pharmacological properties, including:

  • Antimicrobial Activity: Some studies suggest that quinoline derivatives exhibit significant antimicrobial effects, making them candidates for developing new antibiotics.
  • Antitumor Properties: Research indicates that this compound may have potential anticancer effects, prompting investigations into its use in cancer therapy.
  • Enzyme Inhibition: It may work as an enzyme inhibitor, opening doors for research into its role in various biochemical pathways.

Unique Chemical Structure

The unique structure of 6,7-dimethoxyquinolin-4-amine allows it to engage in various chemical reactions. The presence of methoxy groups enhances its solubility and bioavailability, factors that are crucial in drug design. Furthermore, the amine group serves as a versatile site for further functionalization, enabling chemists to tailor the compound for specific purposes.

Application in Research

In the laboratory, this compound is often used as a building block in the synthesis of more complex molecules. Its ability to undergo diverse chemical transformations makes it a valuable asset for chemists aiming to explore new compounds, particularly in the search for novel therapeutic agents.

As quoted by a notable chemist: "The beauty of organic chemistry lies in the endless possibilities that arise from simple modifications to a compound's structure."

In conclusion, 6,7-dimethoxyquinolin-4-amine is more than just a simple molecule — it's a gateway to innovative research and development in the field of medicinal chemistry. Researchers continue to explore its properties, promising exciting possibilities for the future of pharmaceuticals.

Synonyms
Amiquinsin
13425-92-8
4-Amino-6,7-dimethoxyquinoline
Amiquinsine
Amiquinsina
Amiquinsin [INN]
Amiquinsinum
4-Amino-6,7-dimethoxychinolin
4-Quinolinamine, 6,7-dimethoxy-
UNII-85HK85C137
85HK85C137
DTXSID20158613
4-amino-6,7-dimethoxyquinoline hydrochloride, monohydrate
DTXCID3081104
6,7-dimethoxyquinolin-4-amine
SCHEMBL242841
CHEMBL2110601
MFCD00865929
AKOS005188231
SB71822
AC-14532
BS-50519
SY318229
CS-0149228
NS00125880
E76412
Q27269641