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Lidofenin chloride

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Identification
Molecular formula
C19H26ClNO
CAS number
13980-46-6
IUPAC name
6,7-dimethyl-2-(piperidin-1-ium-1-ylmethyl)tetralin-1-one;chloride
State
State
Lidofenin chloride is usually found in a solid state at room temperature, largely existing as a crystalline powder. It is not typically volatile under standard conditions.
Melting point (Celsius)
230.50
Melting point (Kelvin)
503.70
Boiling point (Celsius)
620.40
Boiling point (Kelvin)
893.60
General information
Molecular weight
321.88g/mol
Molar mass
320.8590g/mol
Density
1.0847g/cm3
Appearence

Lidofenin chloride typically appears as a white to slightly off-white crystalline powder. It is known for its hygroscopic nature, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 6,7-dimethyl-2-(piperidin-1-ium-1-ylmethyl)tetralin-1-one; chloride

The solubility of 6,7-dimethyl-2-(piperidin-1-ium-1-ylmethyl)tetralin-1-one; chloride can be understood through several key factors:

  • Polarity: The presence of a piperidine moiety contributes to the overall polarity of the compound, which typically enhances solubility in polar solvents.
  • Hydrophilicity: The ionic nature of the chloride counterion significantly improves solubility in aqueous solutions, especially given that ionic compounds generally dissolve well in water.
  • Hydrogen Bonding: The potential for hydrogen bonding due to nitrogen atoms in the piperidine ring can further facilitate solubility in various solvents.

It is often stated that "like dissolves like," meaning that compounds with similar polarities and functional groups tend to dissolve in each other. Therefore, considering the structure of this compound, it is likely to be soluble in:

  • Water
  • Alcohols
  • Aqueous acidic solutions

In summary, the extensive structural features of 6,7-dimethyl-2-(piperidin-1-ium-1-ylmethyl)tetralin-1-one; chloride suggest that it exhibits good solubility characteristics, particularly in polar solvents due to its ionic nature and hydrogen bond interactions.

Interesting facts

Interesting Facts about 6,7-Dimethyl-2-(piperidin-1-ium-1-ylmethyl)tetralin-1-one; Chloride

This intriguing compound is a member of a broader class of chemicals that have been the focus of intense scientific research due to their potential applications in various fields, including medicinal chemistry.

Applications in Pharmaceutical Research

  • Neuropharmacology: The compound's structural features suggest it may interact with neurotransmitter receptors, making it a candidate for studies on depression or anxiety treatments.
  • Pain Management: Compounds similar to this one have been explored for their analgesic properties, potentially offering less addictive alternatives to traditional opioids.
  • Antiviral Investigations: Certain structural analogs have shown promise in antiviral research, indicating that derivatives of this compound could be valuable in combating viral infections.

Molecular Versatility

The presence of the piperidin-1-ium moiety in its structure enhances the compound's potential for varying chemical reactivity. This allows for:

  • Functionalization at different positions, which can lead to a wide array of derivatives.
  • Exploration of its pharmacokinetic properties, essential for drug development.

Research Challenges

Despite its potential, this compound also presents challenges for researchers:

  • Synthetic Complexity: The multi-step synthesis required to create this compound can complicate its production and scalability.
  • Stability Issues: Its ionic nature may render it sensitive to environmental factors, leading to challenges in storage and handling.

As research continues, the characteristic features and capabilities of 6,7-dimethyl-2-(piperidin-1-ium-1-ylmethyl)tetralin-1-one; chloride will undoubtedly provide valuable insights into new therapeutic avenues and applications. The exploration of its derivatives could open new doors in pharmaceutical innovation.

Synonyms
6,7-Dimethyl-2-piperidinomethyl-1-tetralone hydrochloride
N-702
3,4-Dihydro-6,7-dimethyl-2-piperidinomethyl-1(2H)-napthalenone hydrochloride
1(2H)-NAPHTHALENONE, 3,4-DIHYDRO-6,7-DIMETHYL-2-PIPERIDINOMETHYL-, HYDROCHLORIDE
10275-85-1