Interesting facts
Interesting Facts about 6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic Acid
This compound, known for its complex structure, belongs to the family of quinolone derivatives, which are widely studied due to their potential applications in pharmaceuticals. Here are some intriguing aspects regarding this specific molecule:
- Pharmacological Potential: Quinoline derivatives, including this compound, have been researched for their antimicrobial, antiviral, and anticancer properties, contributing to the development of new therapeutic agents.
- Fluorinated Features: The presence of multiple fluorine atoms enhances the lipophilicity and metabolic stability of the compound, making it a candidate for drugs that require longer durations of action.
- Piperazine Ring: The incorporation of a piperazine moiety is noteworthy as it often imparts favorable pharmacological properties, such as improved binding to biological targets.
- Synthesis Challenges: The synthetic route to achieve the precise substitution pattern in this molecule can be complex and requires advanced techniques in organic chemistry.
- Research Applications: This compound is an example of how medicinal chemistry can modify existing structures to enhance activity or reduce side effects in drug design.
In conclusion, 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid exemplifies the innovation in drug discovery and the importance of fine-tuning chemical structures to achieve specific biological activities. Its unique properties are a reflection of the intricate interplay between molecular design and pharmacology.
Synonyms
fleroxacin
79660-72-3
Megalone
Megalocin
Fleroxicin
Quinodis
Fleroxacino
Fleroxacine
Fleroxacinum
6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
AM-833
Fleroxacine [French]
Fleroxacinum [Latin]
Fleroxacino [Spanish]
Ro 23-6240
Ro 23-6240/000
Megalocin (TN)
Ro-236240
Megalone (TN)
Fleroxacin (Quinodis)
CCRIS 3972
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
CHEBI:31810
MFCD00864880
BRN 4300996
N804LDH51K
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
DTXSID1046714
Ro-236240000
Fleroxacin [USAN:INN:BAN:JAN]
FLEROXACIN [MI]
Ro-23-6240/000
FLEROXACIN [INN]
FLEROXACIN [JAN]
FLEROXACIN [USAN]
3-Quinolinecarboxylic acid, 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
FLEROXACIN [MART.]
FLEROXACIN [WHO-DD]
DTXCID9026714
Fleroxacinum (Latin)
NCGC00167558-01
RO 23-6240;AM-833
AM 833
FLEROXACIN (MART.)
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid
3-Quinolinecarboxylic acid, 1,4-dihydro-6,8-difluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-
Megalosin
6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid-
SMR000466302
CAS-79660-72-3
FLRX
SR-01000759379
UNII-N804LDH51K
Fleroxacin (JAN/USAN/INN)
Fleroxacin,(S)
79660-53-0
F0646
CHEMBL6273
SCHEMBL48145
MLS000759401
MLS006010715
GTPL12476
J01MA08
HMS2090I08
HMS3715B11
BCP28939
HY-B0414
RKL10075
Tox21_112553
BDBM50247892
s2469
ZINC03786299
AKOS015907011
Tox21_112553_1
AF23303
CCG-221125
DB04576
KS-5124
NCGC00167558-02
SY057457
NS00005485
D01716
Fleroxacin, VETRANAL(TM), analytical standard
AB00640001-02
AB00640001-03
AB00640001_04
Q3746573
SR-01000759379-2
SR-01000759379-3
BRD-K61717546-001-04-3
BRD-K61717546-001-05-0
6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid
677-525-2
Solubility of 6,8-Difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic Acid
The solubility of chemical compounds can greatly influence their application in various fields, particularly in pharmaceuticals. For the compound 6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid, characterized by the formula C21H19F3N4O3, the solubility profile is complex and depends on several factors:
Based on its molecular structure, this compound may exhibit good solubility in organic solvents such as DMSO or DMF, while showing variable solubility in water. As solubility can be crucial for bioavailability, understanding these factors is essential for its practical use. Experimental data will determine the exact solubility, but these insights give a foundational understanding of how this compound might behave in solution.