Esculetin | Solubility of Things

Identification

Molecular formula

C₉H₆O₄

CAS number

305-01-1

IUPAC name

6,9-dihydroxybenzofuro[3,2-c]chromen-3-one

State

At room temperature, esculetin is typically in solid state.

Melting point (Celsius)

268.00

Melting point (Kelvin)

541.15

Boiling point (Celsius)

369.69

Boiling point (Kelvin)

642.84

General information

Molecular weight

178.14g/mol

Molar mass

178.1430g/mol

Density

1.5481g/cm³

Appearence

Esculetin appears as a crystalline solid substance. It is a colorless to light yellow powder that may have a slight characteristic odor. Its crystalline nature is often important for its identification and analysis in laboratory settings.

Comment on solubility

Solubility of 6,9-Dihydroxybenzofuro[3,2-c]chromen-3-one

The solubility of 6,9-dihydroxybenzofuro[3,2-c]chromen-3-one is a subject of interest due to its structural uniqueness. This compound typically demonstrates variable solubility, which can be attributed to several factors:

Polarity: The presence of hydroxyl groups (-OH) often indicates that the compound has some polar character, which can enhance its solubility in polar solvents like water.
Solvent Selection: Organic solvents such as ethanol or methanol generally provide better solubility for compounds with aromatic rings.
Temperature Influence: Increasing the temperature often leads to enhanced solubility for a wide range of organic compounds; therefore, careful consideration must be given to experimental conditions.
Interactions: Hydrogen bonding capabilities of the -OH groups can facilitate interactions with solvent molecules, further affecting solubility.

In laboratory settings, it would be advisable to assess the solubility of this compound under various conditions to determine the optimal solvent system. “The solubility characteristics can also influence pharmacokinetics and bioavailability in drug development.”

Overall, while predictions about solubility can be made, empirical data is essential for a comprehensive understanding of how 6,9-dihydroxybenzofuro[3,2-c]chromen-3-one behaves in different environments.

Interesting facts

Interesting Facts about 6,9-Dihydroxybenzofuro[3,2-c]chromen-3-one

6,9-Dihydroxybenzofuro[3,2-c]chromen-3-one, often referred to in the scientific community for its unique structure and promising applications, is a fascinating compound that warrants deeper exploration. Below are some compelling facts that highlight its significance:

Natural Sources: This compound is primarily derived from natural sources, particularly certain plants that are known for their medicinal properties. It has been studied for its potential role in traditional medicine.
Biological Activity: Research indicates that 6,9-dihydroxybenzofuro[3,2-c]chromen-3-one exhibits significant biological activities, including antioxidant, anti-inflammatory, and potential anti-cancer properties. This makes it a subject of interest in pharmacological studies.
Structural Features: The unique fused ring structure of this compound contributes to its reactivity and interactions with biological molecules. Its benzofuro and chromenone parts are noteworthy, giving the compound its distinctive chemical behavior.
Publications & Studies: Numerous studies have been published, indicating its potential applications in drug design and development. Researchers are continuously investigating its effects and mechanisms of action.
Future Research: The ongoing research on this compound holds promise for the development of new therapeutics. Questions regarding its pharmacokinetics and bioavailability are particularly crucial for future studies.

In summary, 6,9-dihydroxybenzofuro[3,2-c]chromen-3-one represents a compound with vast potential in the fields of pharmaceuticals and natural product chemistry. Its diverse range of biological activities and rich structural complexity make it a compelling subject for further research and exploration. As with many compounds of natural origin, its journey from the lab to therapeutic applications is an exciting one!