Cannabidiol (CBD) | Solubility of Things

Identification

Molecular formula

C₂₁H₃₀O₂

CAS number

13956-29-1

IUPAC name

(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

State

CBD exists as a solid at room temperature, with crystalline properties.

Melting point (Celsius)

66.00

Melting point (Kelvin)

339.15

Boiling point (Celsius)

160.00

Boiling point (Kelvin)

433.15

General information

Molecular weight

314.47g/mol

Molar mass

314.4690g/mol

Density

1.0000g/cm³

Appearence

Cannabidiol (CBD) is a crystalline solid that is colorless to pale yellow in appearance. CBD is sometimes available as a pure crystal isolate, a refined white powder form.

Comment on solubility

Solubility of (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

The solubility of (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol can be a complex subject due to its unique structural characteristics. This compound is likely to exhibit variable solubility in different solvents.

Factors Influencing Solubility

Polarity of the Solvent: Nonpolar solvents like hexane might dissolve this compound better than polar solvents such as water.
Molecular Size: The large hydrocarbon structure suggests that its solubility in aqueous solutions may be quite low.
Functional Groups: Any additional functional groups present can also influence solubility; however, in this case, the hydroxyl group may provide some interaction with polar solvents.

As a rule of thumb, “like dissolves like.” Thus, when considering solubility:

If a solvent is polar, it tends to dissolve polar compounds.
If a solvent is nonpolar, it tends to dissolve nonpolar compounds.

In conclusion, while (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol may show limited solubility in water, it is likely soluble in a variety of organic solvents, making it versatile for diverse applications and highlighting its importance in the realm of organic chemistry.

Interesting facts

Interesting Facts about (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

This intriguing compound belongs to a class of chemicals that has aroused interest due to its potential therapeutic effects. Derived from the natural product family, its unique structure allows for a variety of fascinating interactions within biological systems. Here are a few noteworthy points:

Natural Origins: This compound is often found in cannabis plants. Its relation to cannabinoids presents exciting implications for research in pharmacology and medicinal chemistry.
Potential Medicinal Uses: Research has suggested that compounds like this one may exhibit effects such as analgesic, anti-inflammatory, and neuroprotective properties.
Structure-Activity Relationship: The specific stereochemistry denoted by the (6aR,10aR) configuration plays a crucial role in how the molecule interacts with biological targets, influencing its efficacy and safety.
Research Opportunities: As scientists explore its mechanisms, there is ongoing interest in how modifications to its structure might enhance desired properties, leading to the development of novel therapeutic agents.

In summary, (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol is not just a chemical entity but a gateway to understanding the complex interplay of natural compounds and their potential applications in health and wellness. The future looks promising as we delve deeper into its biochemical pathways.

Synonyms

Dronabinol

TETRAHYDROCANNABINOL

delta9-Tetrahydrocannabinol

delta9-THC

delta-9-tetrahydrocannabinol

Deltanyne

Abbott 40566

delta-9-THC

delta(9)-THC

Dronabinolum

THC

delta1-THC

Namisol

delta(1)-Tetrahydrocannabinol

delta(sup 1)-Thc

delta(sup 9)-Thc

QCD 84924

SP 104

delta(9)-Tetrahydrocannabinol

1-trans-delta9-Tetrahydrocannabinol

QCD-84924

Syndros

Dronabinolum [Latin]

delta(9)-Tetrahydrocannibinol

delta(sup 1)-Tetrahydrocannabinol

delta(sup 9)-Tetrahydrocannabinol

L-delta1-trans-Tetrahydrocannabinol

Cannabinol, delta1-tetrahydro-

CCRIS 4726

CHEBI:66964

3-Pentyl-6,6,9-trimethyl-6a,7,8,10a-tetrahydro-6H-dibenzo(b,d)pyran-1-ol

(l)-delta(sup 1)-Tetrahydrocannabinol

NSC-134454

Tetrahydrocannabinols (-)-delta1-3,4-trans-form

ABBOTT-40566

DTXSID6021327

(-)-delta9-Tetrahydrocannabinol

1-trans-delta(sup 9)-Tetrahydrocannabinol

HSDB 6471

J882F

Cannabinol, 1-trans-delta(sup 9)-tetrahydro-

(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol

SP-104

7J8897W37S

NSC 134454

(-)-delta(sup 1)-3,4-trans-Tetrahydrocannabinol

delta 9-Tetrahydrocannabinol

delta-9 Tetrahydrocannabinol

6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-

DTXCID101327

UNII-7J8897W37S

Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol

6,6,9-Trimethyl-3-pentyl-7,8,9,10-tetrahydro-6H-dibenzo(b,d)pyran-1-ol

NSC134454

6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR,10aR)-

Dronabinolum (Latin)

delta(1)-THC

TETRAHYDROCANNABINOL, DELTA-9 TRANS

DRONABINOL (MART.)

DRONABINOL [MART.]

(6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol

9-ene-Tetrahydrocannabinol

Dronabinol (USAN:USP:INN)

Dronabinol [USAN:USP:INN]

DRONABINOL (USP MONOGRAPH)

DRONABINOL [USP MONOGRAPH]

(6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol

6H-dibenzo[b,d]pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR,10aR)-

(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-DIBENZO(B,D)PYRAN-1-OL

9 ene Tetrahydrocannabinol

(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo(c)chromen-1-ol

6H-Dibenzo[b,d]pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-

delta 1-Tetrahydrocannabinol

A04AD10

(-)-delta 9-trans-Tetrahydrocannabinol

(-)-delta1-3,4-trans-Tetrahydrocannabinol

TETRAHYDROCANNABINOLS (-)-TRANS-delta9-FORM

(6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo

(6aR-trans)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo

Marinol

1972-08-3

1-trans-delta-9-Tetrahydrocannabinol

(-)-delta9-trans-Tetrahydrocannabinol

9-tetrahydrocannabinol

delta1-Tetrahydrocannabinol

.DELTA.9-Tetrahydrocannabinol

.DELTA.1-THC

.DELTA.9-THC

6465-30-1

CHEMBL465

(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

.delta.-9-tetrahydrocannabinol

6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol

trans-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol

Tetrahydrocannabinols (-)-trans-.delta.9-form

6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-

(-)-.DELTA.9-THC

Compassia

Relivar

(L)-.delta.1-Tetrahydrocannabinol

(-)-.DELTA.1-Tetrahydrocannabinol

(-)-.DELTA.9-Tetrahydrocannabinol

L-.delta.1-trans-Tetrahydrocannabinol

L-trans-.delta.9-Tetrahydrocannabinol

Delta 9-THC

(6aR-trans)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol

(-)-.DELTA.9-trans-Tetrahydrocannabinol

(-)-trans-.DELTA.9-Tetrahydrocannabinol

Marinol (TN)

DEA No. 7369

delta1-Tetrahydrocannabinol (VAN)

delta9-Tetrahydrocannabinol (VAN)

Dronabinol (USP/INN)

.DELTA.1-Tetrahydrocannabinol

Tetrahydrocannabinol delta9

(-)-trans-Delta9-THC

Cannabinol, .DELTA.1-tetrahydro-

.DELTA.9-trans-Tetrahydrocannabinol

(l)-delta1-Tetrahydrocannabinol

L-.delta.1-Tetrahydrocannabinol

(-)-delta1-Tetrahydrocannabinol

delta9-trans-Tetrahydrocannabinol

trans-delta9-Tetrahydrocannabinol

(6aR-trans)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol

CAT-310

L-trans-delta9-Tetrahydrocannabinol

DRG-0138

TCI

14C-.DELTA.1-Tetrahydrocannabinol

trans-.DELTA.9-Tetrahydrocannabinol

(-)-trans-Delta1-Tetrahydrocannabinol

(-)-trans-delta9-Tetrahydrocannabinol

.delta.-9-THC

1-trans-delta(sup9)-tetrahydrocannabinol

Dronabinol (Synthetic)

.delta.(sup9)-THC

3ls4

DRONABINOL [INN]

(-)-3,4-trans-Delta1-Tetrahydrocannabinol

1-trans-.delta.(sup9)-tetrahydrocannabinol

DRONABINOL [HSDB]

DRONABINOL [USAN]

(-)-.delta.(sup9)-trans-Tetrahydrocannabinol

DRONABINOL [VANDF]

Epitope ID:224552

SCHEMBL4609

AD313 component dronabinol

DRONABINOL [WHO-DD]

AD-313 component dronabinol

BIDD:GT0427

SCI-110 component dronabinol

GTPL2424

Cannabinol, tetrahydro- (6CI)

DRONABINOL [ORANGE BOOK]

BDBM60994

delta-Tetrahydrocannabinol (THC)

DTXSID001038830

US9416103, Delta9-THC

INT-0010

(A+/-)-delta9-Tetrahydrocannabinol

Tox21_112616

BDBM50007391

PDSP2_000714

Cannabinol, Delta1-tetrahydro- (7CI)

DB00470

FT28083

INT-0010/06

CAS-1972-08-3

NS00000050

C06972

Cannabinol, 1-trans-.delta.(sup9)-tetrahydro-

D00306

Q190067

(-)-.DELTA.1-3,4-TRANS-TETRAHYDROCANNABINOL

(-)-Delta9-THC (Dronabinol) 0.1 mg/ml in Methanol

(-)-Delta9-THC (Dronabinol) 1.0 mg/ml in Methanol

(-)-Delta-9-THC (Dronabinol) 5.0 mg/ml in Methanol

(-)-trans-Delta-9-THC (Dronabinol), 100mg/ml in Ethanol

(-)-trans-Delta-9-THC (Dronabinol), 10mg/ml in Ethanol

(-)-trans-Delta-9-THC (Dronabinol), 1mg/ml in Ethanol

(-)-trans-Delta-9-THC (Dronabinol), 50mg/ml in Ethanol

Delta9-Tetrahydrocannabinol 250 microg/mL in Acetonitrile

TETRAHYDROCANNABINOLS (-)-TRANS-.DELTA.9-FORM [MI]

6H-Dibenzo[b, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-

(-)-delta 9-Tetrahydrocannabinol (delta9-THC) 1000 microg/mL in Methanol

(-)-Delta9-Tetrahydrocannabinol (Delta9-THC) 100 microg/mL in Methanol

6,9-Trimethyl-3-pentyl-7,8,9,10-tetrahydro-6H-dibenzo[b,d]pyran-1-ol

6H-Dibenzo[b, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, trans-

(-)-(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol

(-)-delta(sup 1)-3,4-trans-Tetrahydrocannabinol(l)-delta(sup 1)-Tetrahydrocannabinol

(10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol

(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6H,6AH,7H,8H,10AH-BENZO[C]ISOCHROMEN-1-OL

(S)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol

6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol(DeltaE-9-THC)

6H-Dibenzo[b, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-

Delta-9-Tetrahydrocannabinol, United States Pharmacopeia (USP) Reference Standard

6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol(delta9-THC(delta9-tetrahydrocannabinol))

8,8-Dimethyl-11-methylene-5-pentyl-3,4,8a,9,10,11,12,12a-octahydro-2H,8H-1,7-dioxa-benzo[c]phenanthrene