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Δ9-Tetrahydrocannabinol (THC)

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Identification
Molecular formula
C21H30O2
CAS number
1972-08-3
IUPAC name
(6aR,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
State
State

THC is typically found in a viscous, oily state at room temperature. It is lipophilic, dissolving in fats and oils rather than water.

Melting point (Celsius)
-3.00
Melting point (Kelvin)
269.15
Boiling point (Celsius)
157.00
Boiling point (Kelvin)
430.15
General information
Molecular weight
314.46g/mol
Molar mass
314.4640g/mol
Density
1.0040g/cm3
Appearence

Δ9-Tetrahydrocannabinol, commonly known as THC, appears as a colorless, sticky resin when isolated. When diluted or part of cannabis extracts, it can appear as a viscous oil ranging in color from light amber to dark brown depending on purity and concentration.

Comment on solubility

Solubility Overview

The compound (6aR,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol exhibits unique solubility characteristics which primarily depend on its molecular structure and functional groups.

Key Solubility Characteristics:

  • Nonpolar Nature: Due to its extensive hydrocarbon framework, the compound is generally nonpolar.
  • Solvent Compatibility: It is likely to be soluble in organic solvents such as:
    • Hexane
    • Chloroform
    • Ethyl acetate
  • Water Solubility: Expect a low solubility in water based on its hydrophobic characteristics.

The solubility of this compound could significantly impact its applications, particularly in the field of pharmacology where solubility influences bioavailability. As with many similar compounds, the specific interactions with solvents must be experimentally determined for precise applications.

Overall, understanding the solubility of (6aR,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol can provide insight into its potential uses in various chemical and biological systems.

Interesting facts

Interesting Facts about (6aR,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol

This fascinating compound is part of a larger family of chemical substances known as cannabinoids, which have garnered much interest in the fields of chemistry and medicine. Here are some intriguing aspects of this compound:

  • Structural Complexity: The compound showcases a unique structure, characterized by its multiple methyl groups and the intricate arrangement of its atoms. This structural complexity is pivotal in influencing its chemical properties and biological activities.
  • Natural Origins: Many cannabinoids, including this one, are found in the cannabis plant. They are synthesized through biosynthetic pathways that involve complex enzymatic reactions, fascinating chemistries that are still being unraveled.
  • Potential Therapeutic Uses: Research has suggested that compounds like this one exhibit various pharmacological effects. They may have potential applications in treating conditions such as inflammation, pain, and perhaps even certain neurodegenerative diseases.
  • Isomeric Diversity: As a chiral compound, it exists in multiple isomeric forms. This aspect is crucial, as different enantiomers might exhibit varying degrees of efficacy, safety, and side effects in therapeutic settings.
  • Research Frontiers: The study of this compound and others in its class is at the forefront of pharmacology and biochemistry. Scientists are keenly investigating their mechanisms of action, receptor interactions, and metabolic pathways to unlock new avenues for drug discovery.

As a reminder of its significance, a prominent researcher once noted, "The chemistry of cannabinoids is not just about understanding their structure, but about discovering their potential to change lives." The exploration of such compounds continues to present exciting opportunities in both basic and applied sciences.

Overall, the complexities and therapeutic potential of (6aR,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol make it a compound of substantial interest for future research and application.

Synonyms
dl-cis-delta(sup 9)-Thc
6H-Dibenzo(b,d)pyran-1-ol, 6a-beta,7,8,10-a-beta-tetrahydro-3-pentyl-6,6,9-trimethyl-, (+-)-Z-
DTXSID00209718
DTXCID50132209
6087-73-6
(6aR,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
CHEMBL4862731
(?)-cis-?9-THC
SCHEMBL22705549
SCHEMBL24702729
BDBM50577908