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Ibogaine

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Identification
Molecular formula
C20H26BrN3O
CAS number
83-74-9
IUPAC name
(6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
State
State

At room temperature, ibogaine is typically found as a solid substance. In its extracted and refined form, it usually manifests as a white, powdery crystalline substance.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.00
Boiling point (Celsius)
291.00
Boiling point (Kelvin)
564.00
General information
Molecular weight
310.35g/mol
Molar mass
310.1900g/mol
Density
1.4500g/cm3
Appearence

Ibogaine is a naturally occurring psychoactive substance found in plants. As a chemical compound, it is generally a crystalline solid. The pure form of ibogaine appears as powdery white crystals, while crude extracts may be brownish orange in color due to impurities.

Comment on solubility

Solubility of (6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

The solubility of (6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide is an essential aspect to consider in various applications, especially in pharmaceuticals and chemical synthesis. Understanding its solubility behavior can reveal crucial information about its usability:

  • Solubility in Water: This compound may exhibit low solubility in water due to its complex structure and the presence of hydrophobic groups, which can hinder interactions with water molecules.
  • Solubility in Organic Solvents: It is likely to show better solubility in organic solvents such as DMSO or DMF, which can stabilize the compound due to polar interactions.
  • pH Dependence: The solubility may also vary with pH changes; therefore, it is crucial to assess how different environments affect the compound's solubility.
  • Practical Applications: Knowledge of solubility is key for formulation development, as it impacts bioavailability and efficacy in drug applications.

In conclusion, the solubility of (6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide is a multifaceted topic that plays a vital role in its chemical behavior and practical uses. Exploring this aspect can lead to improved understanding and innovative applications in various fields.

Interesting facts

Interesting Facts about (6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide

This unique compound represents a fascinating area of study due to its complex structure and potential applications. As a member of the indole family, it features intricate fused ring systems that exhibit a range of chemical behaviors. Here are some notable points about this compound:

  • Structural Complexity: The presence of multiple rings and various functional groups contributes to its rich chemistry, making it a subject of interest in fields such as medicinal chemistry and material science.
  • Biological Activity: Compounds like this one are often explored for their pharmacological properties. Indole derivatives have been known to exhibit a variety of biological activities, including antitumor and antibacterial effects.
  • Applications in Research: Due to their diverse reactivity, tetrahydroquinolines are often utilized as intermediates in the synthesis of a wide array of biologically active molecules.
  • Potential Therapeutic Uses: Some studies suggest that compounds with similar structures could act as modulators for certain diseases, highlighting the importance of structure-activity relationships in drug development.
  • Synthetic Pathways: The synthesis of such compounds often involves intricate multi-step procedures, showcasing the ingenuity required in organic synthesis and promoting further exploration in synthetic methodologies.

In summary, (6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide exemplifies the intersection of complexity and functionality in organic compounds. As research continues, compounds like these may open new avenues for drug discovery and development, solidifying their significance in the scientific community.

Synonyms
BROMOLYSERGIDE
2-Bromo-LSD
478-84-2
Bromlysergamide
Brom LSD
BOL-148
2-Br-LSD
USAF SZ-1
2-Bromo-D-lysergic acid diethylamide
D-2-Bromolysergic acid diethylamide
2-Brom-D-lysergic acid diethylamine
BROMOLYSERGIDE [MI]
D-2-Brom-diethylamide of lysergic acid
DTXSID30878496
Bromolysergic acid diethylamide
(6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide
2-BROMO-N,N-DIETHYL-D-LYSERGAMIDE
2-Bromo-9,10-didehydro-N,N-diethyl-6-methylergoline-8-beta-carboxamide
9,10-Didehydro-N,N-diethyl-2-bromo-6-methylergoline-8-beta-carboxamide
Ergoline-8-beta-carboxamide, 2-bromo-9,10-didehydro-N,N-diethyl-6-methyl-
(8beta)-2-bromo-9,10-didehydro-n,n-diethyl-6-methylergoline-8-carboxamide
(6aR,9R)-5-bromo-N,N-diethyl-7-methyl-6,6a,8,9-tetrahydro-4H-indolo(4,3-fg)quinoline-9-carboxamide
DTXCID101016542
2-Bromolysergic acid diethylamide
Bromo-LSD
JUA77QEU32
CHEMBL274384
A1AFU
Ergoline-8-carboxamide, 2-bromo-9,10-didehydro-N,N-diethyl-6-methyl-, (8beta)-
BOL-148; Bromolysergic Acid diethylamide; Bromolysergide; 2-bromo-9,10-didehydro-N,N-diethyl-6-methyl-ergoline-8ss-carboxamide
LSD,2-Bromo
UNII-JUA77QEU32
GTPL272
BOL148
SCHEMBL1883414
VKRAXSZEDRWLAG-SJKOYZFVSA-N
BDBM50130269
AKOS040748061
PD052069
HY-121675
Q4596865
(6aR,9R)-5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide
(6aR,9R)-5-Bromo-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide