Skip to main content

Vincristine tartrate

ADVERTISEMENT
Identification
Molecular formula
C46H56N4O10
CAS number
57-22-7
IUPAC name
(6aR,9R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide;(2R,3R)-2,3-dihydroxybutanedioic acid
State
State

At room temperature, vincristine tartrate is in a solid state. It is typically handled under controlled conditions in a laboratory or clinical environment.

Melting point (Celsius)
218.00
Melting point (Kelvin)
491.00
Boiling point (Celsius)
-60.00
Boiling point (Kelvin)
213.00
General information
Molecular weight
923.05g/mol
Molar mass
923.0480g/mol
Density
1.4500g/cm3
Appearence

Vincristine tartrate is a white to slightly yellow powder. It is often presented in its solid state as a lyophilized powder for injection in pharmaceutical settings.

Comment on solubility

Solubility of the Compound

The solubility of the compound (6aR,9R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide; (2R,3R)-2,3-dihydroxybutanedioic acid can be intriguing due to its complex molecular structure and the interplay between the various functional groups present.

Factors impacting its solubility include:

  • Polarity: The presence of hydroxyl groups and carboxamide moieties can enhance solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds can significantly increase its affinity for aqueous environments.
  • Molecular Weight: A high molecular weight may lead to lower solubility due to reduced ability to interact with solvent molecules.
  • Intermolecular Interactions: Pi-stacking and van der Waals forces may influence how the compound interacts with solvents.

In summary, while the exact solubility in different solvents may vary, it is clear that the intricate balance of hydrophilic and hydrophobic characteristics plays a crucial role. As the old adage goes, "Like dissolves like," meaning that a careful consideration of solvent properties will provide insights into the solubility behavior of this fascinating compound.

Interesting facts

Interesting Facts about (6aR,9R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.02,6]dodecan-4-yl]-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide; (2R,3R)-2,3-dihydroxybutanedioic acid

The compound in discussion is a fascinating example of complex organic chemistry. It showcases a unique dual structure that combines elements of both idoloquinoline and dihydroxybutanedioic acid, making it a compound of interest in various research fields.

Structural Highlights

  • Diverse Functional Groups: The compound possesses multiple functional groups, including carboxamide and hydroxyl groups, which contribute to its chemical reactivity and potential applications.
  • Stereochemistry: The presence of stereocenters in both sections of the compound indicates profound chirality. This feature can dramatically influence the biological activity of the compound.
  • Multi-ring System: The intricate ring structure of the indoloquinoline part emphasizes the complexity and potential for engaging in various chemical interactions.

Biological Significance

Compounds like this are often studied for their potential pharmacological properties. Specifically, the indoloquinoline derivatives have been researched for:

  • Antimicrobial activity
  • Anticancer properties
  • Neuroprotective effects

Innovative Applications

With the presence of the 2,3-dihydroxybutanedioic acid moiety, this compound also stands to contribute to advances in:

  • Biochemistry, particularly in metabolic pathways
  • Drug formulation processes where synergy between components is crucial

Interestingly, the study of such complex molecules can open new avenues in medicinal chemistry, driving forward the development of novel therapeutics. As noted by chemists, "The beauty of organic compounds lies in their endless variability and the profound impacts they can have on our health and environment."


Synonyms
24381-56-4
Ergotamine, tartrate
Ergotamine, tartrate (1:1) salt
DTXSID60947245
379E793
2,3-Dihydroxybutanedioic acid--N-(5-benzyl-10b-hydroxy-2-methyl-3,6-dioxooctahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-6-methyl-9,10-didehydroergoline-8-carboximidic acid (1/1)